Effect of Endocervical-Specimen Adequacy on Detection of Chlamydia trachomatis by the APTIMA COMBO 2 Assay

Six hundred one endocervical specimens were analyzed for Chlamydia trachomatis by the APTIMA Combo 2 assay and evaluated for columnar epithelial cell adequacy by direct fluorescent-antibody staining. With 5.5% positive adequate and 7.8% positive inadequate specimens (P = 0.27), the study suggested n...

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Veröffentlicht in:Journal of Clinical Microbiology 2006-12, Vol.44 (12), p.4564-4565
Hauptverfasser: Rogers, C.K, Wood, B.J, Rizzo, P, Gaydos, C.A
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container_end_page 4565
container_issue 12
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container_title Journal of Clinical Microbiology
container_volume 44
creator Rogers, C.K
Wood, B.J
Rizzo, P
Gaydos, C.A
description Six hundred one endocervical specimens were analyzed for Chlamydia trachomatis by the APTIMA Combo 2 assay and evaluated for columnar epithelial cell adequacy by direct fluorescent-antibody staining. With 5.5% positive adequate and 7.8% positive inadequate specimens (P = 0.27), the study suggested no difference in positivity rates due to specimen adequacy when this amplified technology was used.
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source American Society for Microbiology; MEDLINE; EZB-FREE-00999 freely available EZB journals; PubMed Central
subjects Bacteriology
Biological and medical sciences
Cervix Uteri - cytology
Cervix Uteri - microbiology
Chlamydia Infections - diagnosis
Chlamydia Infections - microbiology
Chlamydia trachomatis
Chlamydia trachomatis - isolation & purification
Chlamydiology and Rickettsiology
Epithelial Cells - cytology
Epithelial Cells - microbiology
Female
Fluorescent Antibody Technique
Fundamental and applied biological sciences. Psychology
Humans
Infectious diseases
Medical sciences
Microbiology
Miscellaneous
Reagent Kits, Diagnostic
Sensitivity and Specificity
Specimen Handling
Staining and Labeling
title Effect of Endocervical-Specimen Adequacy on Detection of Chlamydia trachomatis by the APTIMA COMBO 2 Assay
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