Effect of Endocervical-Specimen Adequacy on Detection of Chlamydia trachomatis by the APTIMA COMBO 2 Assay

Six hundred one endocervical specimens were analyzed for Chlamydia trachomatis by the APTIMA Combo 2 assay and evaluated for columnar epithelial cell adequacy by direct fluorescent-antibody staining. With 5.5% positive adequate and 7.8% positive inadequate specimens (P = 0.27), the study suggested n...

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Veröffentlicht in:	Journal of Clinical Microbiology 2006-12, Vol.44 (12), p.4564-4565
Hauptverfasser:	Rogers, C.K, Wood, B.J, Rizzo, P, Gaydos, C.A
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteriology Biological and medical sciences Cervix Uteri - cytology Cervix Uteri - microbiology Chlamydia Infections - diagnosis Chlamydia Infections - microbiology Chlamydia trachomatis Chlamydia trachomatis - isolation & purification Chlamydiology and Rickettsiology Epithelial Cells - cytology Epithelial Cells - microbiology Female Fluorescent Antibody Technique Fundamental and applied biological sciences. Psychology Humans Infectious diseases Medical sciences Microbiology Miscellaneous Reagent Kits, Diagnostic Sensitivity and Specificity Specimen Handling Staining and Labeling
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Zusammenfassung:	Six hundred one endocervical specimens were analyzed for Chlamydia trachomatis by the APTIMA Combo 2 assay and evaluated for columnar epithelial cell adequacy by direct fluorescent-antibody staining. With 5.5% positive adequate and 7.8% positive inadequate specimens (P = 0.27), the study suggested no difference in positivity rates due to specimen adequacy when this amplified technology was used.
ISSN:	0095-1137 1098-660X 1098-5530
DOI:	10.1128/JCM.00981-06