Near-infrared light and pH-responsive Au@carbon/calcium phosphate nanoparticles for imaging and chemo-photothermal cancer therapy of cancer cells

Near-infrared light and pH-responsive Au@carbon/calcium phosphate nanoparticles for imaging and chemo-photothermal cancer therapy of cancer cells

A simple, mild and reproducible synthetic route was developed to fabricate the multifunctional Au@carbon/calcium phosphate core-shell nanoparticles (Au@C/CaP NPs), which act as an efficient nanoplatform for pH/near-infrared (NIR) dual-responsive drug delivery, X-ray computed tomography (CT) imaging...

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Veröffentlicht in:Dalton transactions : an international journal of inorganic chemistry 2017, Vol.46 (43), p.14746-14751
Hauptverfasser: Wang, Huiyuan, Zhang, Manjie, Zhang, Lingyu, Li, Shengnan, Li, Lu, Li, Xiliang, Yu, Min, Mou, Zhongcheng, Wang, Tingting, Wang, Chungang, Su, Zhongmin
Format: Artikel
Sprache:eng
Schlagworte:
Calcium
Calcium phosphates
Cancer
Cancer therapies
Computed tomography
Drug delivery systems
Gold
Infrared radiation
Medical imaging
Nanoparticles
Therapy
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Beschreibung
Zusammenfassung:A simple, mild and reproducible synthetic route was developed to fabricate the multifunctional Au@carbon/calcium phosphate core-shell nanoparticles (Au@C/CaP NPs), which act as an efficient nanoplatform for pH/near-infrared (NIR) dual-responsive drug delivery, X-ray computed tomography (CT) imaging and synergistic chemo-photothermal cancer therapy in vitro.
ISSN:1477-9226
1477-9234
DOI:10.1039/c7dt02274c