Centrifugal micropipette-tip with pressure signal readout for portable quantitative detection of myoglobin

This paper describes a centrifugal micropipette-tip method for ELISA sample processing combined with a pressure meter for portable quantitative detection of acute myocardial infarction (AMI) biomarker myoglobin (Myo). The method enables sensitive and reliable quantification of Myo in 35 minutes. Wit...

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Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2017-08, Vol.53 (86), p.11774-11777
Hauptverfasser:	Song, Yanling, An, Yuan, Liu, Weizhi, Hou, Wanfu, Li, Xingrui, Lin, Bingqian, Zhu, Zhi, Ge, Shengxiang, Yang, Huang-Hao, Yang, Chaoyong
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers - analysis Centrifugation - instrumentation Centrifugation - methods Enzyme-Linked Immunosorbent Assay - instrumentation Enzyme-Linked Immunosorbent Assay - methods Humans Myocardial Infarction - diagnosis Myoglobin - analysis Pressure
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Beschreibung
Zusammenfassung:	This paper describes a centrifugal micropipette-tip method for ELISA sample processing combined with a pressure meter for portable quantitative detection of acute myocardial infarction (AMI) biomarker myoglobin (Myo). The method enables sensitive and reliable quantification of Myo in 35 minutes. With the advantages of simplicity, speed, user friendliness, low cost, and small sample consumption, centrifugal micropipette-tip ELISA shows great potential for quantitative POC diagnostics for AMI.
ISSN:	1359-7345 1364-548X
DOI:	10.1039/c7cc07231g