3D printing hydrogel with graphene oxide is functional in cartilage protection by influencing the signal pathway of Rank/Rankl/OPG

3Dprinting is defined as the use of printing technology to deposit living cells, and biomaterials on a given /a substrate. Graphene oxide nanoparticles (GO-np) have been used as a delivery vehicle for small molecule drugs in order to investigate the state of GO-np within 3D tissue constructs in term...

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Veröffentlicht in:	Materials Science & Engineering C 2018-01, Vol.82, p.244-252
Hauptverfasser:	Cheng, Zhong, Landish, Bolaky, Chi, Zhang, Nannan, Cui, Jingyu, Du, Sen, Lu, Xiangjin, Lin
Format:	Artikel
Sprache:	eng
Schlagworte:	3-D printers 3D printing Animals Biocompatible Materials - chemistry Biocompatible Materials - pharmacology Biomaterials Biomedical materials Bone Morphogenetic Protein 7 - chemistry Bone Morphogenetic Protein 7 - metabolism Bone Morphogenetic Protein 7 - pharmacology Cartilage Cartilage - drug effects Cartilage - metabolism Cell Line Cell Survival - drug effects Chondrocytes Chondrocytes - cytology Chondrocytes - drug effects Chondrocytes - metabolism Drug Carriers - chemistry Drug delivery systems Drugs Graphene Graphene oxide Graphite - chemistry Humans Hydrogels Hydrogels - chemistry Male Materials science Nanoparticles Nanoparticles - chemistry Osteoprotegerin Osteoprotegerin - metabolism Oxides - chemistry Printing Rank RANK Ligand - metabolism Rats Rats, Sprague-Dawley Receptor Activator of Nuclear Factor-kappa B - metabolism Signal Transduction - drug effects Studies Three dimensional composites Three dimensional printing Tissue Scaffolds - chemistry TRANCE protein
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