Intensive chemotherapy improved treatment outcome for Chinese children and adolescents with lymphoblastic lymphoma

Background Lymphoblastic lymphoma (LBL) is a highly aggressive lymphoma, for which intensive chemotherapy is necessary. This study was designed to evaluate the efficacy and toxicity of a modified acute lymphoblastic leukemia (ALL)-Berlin-Frankfurt-Münster (BFM)-90-based protocol in Chinese children...

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Veröffentlicht in:	International journal of clinical oncology 2008-10, Vol.13 (5), p.436-441
Hauptverfasser:	Sun, Xiao-Fei, Xia, Zhong-Jun, Zhen, Zi-Jun, Xiang, Xiao-Juan, Xia, Yi, Ling, Jia-Yu, Liu, Dong-Gen, Huang, Hui-Qiang, Zhen, Lei, Luo, Wen-Biao, Lin, Hui, Guan, Zhong-Zhen
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Antineoplastic Combined Chemotherapy Protocols - adverse effects Antineoplastic Combined Chemotherapy Protocols - therapeutic use Cancer Research Chemotherapy Child Child, Preschool Children & youth Clinical outcomes Drug Administration Schedule Humans Injections, Spinal Leucovorin - administration & dosage Lymphoma Medicine Medicine & Public Health Methotrexate - administration & dosage Oncology Original Article Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy Surgical Oncology Treatment Outcome
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Zusammenfassung:	Background Lymphoblastic lymphoma (LBL) is a highly aggressive lymphoma, for which intensive chemotherapy is necessary. This study was designed to evaluate the efficacy and toxicity of a modified acute lymphoblastic leukemia (ALL)-Berlin-Frankfurt-Münster (BFM)-90-based protocol in Chinese children and adolescents with LBL. Methods From March 1998 to November 2006, 60 untreated patients with LBL (age
ISSN:	1341-9625 1437-7772
DOI:	10.1007/s10147-008-0771-5