Sex-specific kinetic and kinematic indicators of medial tibiofemoral force during walking and running

Our aims were to (1) Evaluate sex-specific contributions of peak knee flexion moment (pKFM) and peak knee adduction moment (pKAM) in medial tibiofemoral joint (TFJ) force during walking and running; (2) identify kinematic variables to estimate peak medial TFJ force. Eighty-seven runners participated (36 females, 51 males; age=23.0±3.8years (1 standard deviation)). Kinematics and kinetics data were collected during treadmill walking (1.3m/s) and running (3.0±0.4m/s). Peak medial TFJ contact force was estimated using a musculoskeletal model. Linear regression analyses were used to assess the contribution of pKFM, pKAM and kinematic indicators to estimated joint forces. During walking and running, pKAM and pKFM accounted for 74.9% and 64.5% of peak medial TFJ force variance (P