Effects of Neuroactive Drugs in the Discharge Patterns of Microsternarchus (Hypopomidae: Gymnotiformes) Electric Organ

Considering the conserved nature of synaptic physiology among vertebrates, we tested the effects of three psychotropics (diazepam, doxapram, and nicotine) on Microsternarchus cf. bilineatus , measuring 10 parameters associated to the electric organ discharges rhythm and waveform before and after the...

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Veröffentlicht in:	Zebrafish 2017-12, Vol.14 (6), p.526-535
Hauptverfasser:	de Jesus, Isac Silva, Ferreira, Milena, Silva-Júnior, Urbano Lopes, Alves-Gomes, José Antônio
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anticonvulsants - pharmacology Behavior, Animal - drug effects Central nervous system Central Nervous System - drug effects Central Nervous System Stimulants - pharmacology Diazepam Diazepam - pharmacology Doxapram - pharmacology Drugs Electric instruments Electric Organ - drug effects Electric organs Firing pattern Firing rate Gymnotiformes Gymnotiformes - physiology Hypopomidae Microsternarchus Nicotine Nicotine - pharmacology Nicotinic Agonists - pharmacology Research Papers Statistical analysis Vertebrates
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Zusammenfassung:	Considering the conserved nature of synaptic physiology among vertebrates, we tested the effects of three psychotropics (diazepam, doxapram, and nicotine) on Microsternarchus cf. bilineatus , measuring 10 parameters associated to the electric organ discharges rhythm and waveform before and after the administration of each drug and a control group. There were statistically significant differences ( p
ISSN:	1545-8547 1557-8542
DOI:	10.1089/zeb.2017.1459