The first reported case and management of multicentric Castleman's disease associated with Kaposi's sarcoma in an HIV-2-infected patient

The multicentric variant of plasma-cell Castleman's disease (MCD) often coexists with Kaposi's sarcoma (KS) in HIV-1-infected patients, and this association could be explained by the possible involvement of human herpes virus 8 (HHV-8) in their pathogenesis. MCD has never been described in...

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Veröffentlicht in:AIDS (London) 2007-07, Vol.21 (11), p.1492-1494
Hauptverfasser: SOPHIE, Bouvresse, ANNE-GENEVIEVE, Marcelin, NATHALIE, Franck, STEPHANIE, Regnier, FLORENCE, Damond, MICHELINE, Tulliez, NICOLAS, Dupin
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container_end_page 1494
container_issue 11
container_start_page 1492
container_title AIDS (London)
container_volume 21
creator SOPHIE, Bouvresse
ANNE-GENEVIEVE, Marcelin
NATHALIE, Franck
STEPHANIE, Regnier
FLORENCE, Damond
MICHELINE, Tulliez
NICOLAS, Dupin
description The multicentric variant of plasma-cell Castleman's disease (MCD) often coexists with Kaposi's sarcoma (KS) in HIV-1-infected patients, and this association could be explained by the possible involvement of human herpes virus 8 (HHV-8) in their pathogenesis. MCD has never been described in an HIV-2-infected patient. We report the first case of MCD associated with HIV type 2 infection and its successful management with rituximab.
doi_str_mv 10.1097/QAD.0b013e3281df33fc
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MCD has never been described in an HIV-2-infected patient. We report the first case of MCD associated with HIV type 2 infection and its successful management with rituximab.</description><identifier>ISSN: 0269-9370</identifier><identifier>EISSN: 1473-5571</identifier><identifier>DOI: 10.1097/QAD.0b013e3281df33fc</identifier><identifier>PMID: 17589201</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott Williams &amp; Wilkins</publisher><subject>Acquired Immunodeficiency Syndrome - complications ; Acquired Immunodeficiency Syndrome - drug therapy ; Acquired Immunodeficiency Syndrome - virology ; Antibodies, Monoclonal - therapeutic use ; Antibodies, Monoclonal, Murine-Derived ; Antineoplastic Agents - therapeutic use ; Biological and medical sciences ; Castleman Disease - complications ; Castleman Disease - drug therapy ; Dermatology ; Hematologic and hematopoietic diseases ; Herpesvirus ; Herpesvirus 8, Human ; HIV-2 ; Human herpesvirus 8 ; Human immunodeficiency virus ; Human viral diseases ; Humans ; Infectious diseases ; Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis ; Lymph Nodes - virology ; Male ; Medical sciences ; Middle Aged ; Rituximab ; Sarcoma, Kaposi - complications ; Sarcoma, Kaposi - drug therapy ; Tumors of the skin and soft tissue. Premalignant lesions ; Viral diseases ; Viral diseases of the lymphoid tissue and the blood. 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Malignant lymphomas. Malignant reticulosis. Myelofibrosis</subject><subject>Lymph Nodes - virology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Rituximab</subject><subject>Sarcoma, Kaposi - complications</subject><subject>Sarcoma, Kaposi - drug therapy</subject><subject>Tumors of the skin and soft tissue. Premalignant lesions</subject><subject>Viral diseases</subject><subject>Viral diseases of the lymphoid tissue and the blood. 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source MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Journals@Ovid Ovid Autoload
subjects Acquired Immunodeficiency Syndrome - complications
Acquired Immunodeficiency Syndrome - drug therapy
Acquired Immunodeficiency Syndrome - virology
Antibodies, Monoclonal - therapeutic use
Antibodies, Monoclonal, Murine-Derived
Antineoplastic Agents - therapeutic use
Biological and medical sciences
Castleman Disease - complications
Castleman Disease - drug therapy
Dermatology
Hematologic and hematopoietic diseases
Herpesvirus
Herpesvirus 8, Human
HIV-2
Human herpesvirus 8
Human immunodeficiency virus
Human viral diseases
Humans
Infectious diseases
Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
Lymph Nodes - virology
Male
Medical sciences
Middle Aged
Rituximab
Sarcoma, Kaposi - complications
Sarcoma, Kaposi - drug therapy
Tumors of the skin and soft tissue. Premalignant lesions
Viral diseases
Viral diseases of the lymphoid tissue and the blood. Aids
title The first reported case and management of multicentric Castleman's disease associated with Kaposi's sarcoma in an HIV-2-infected patient
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