Purity of islet preparations and 5‐year metabolic outcome of allogenic islet transplantation

In allogenic islet transplantation (IT), high purity of islet preparations and low contamination by nonislet cells are generally favored. The aim of the present study was to analyze the relation between the purity of transplanted preparations and graft function during 5 years post‐IT. Twenty‐four pa...

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Veröffentlicht in:American journal of transplantation 2018-04, Vol.18 (4), p.945-951
Hauptverfasser: Benomar, K., Chetboun, M., Espiard, S., Jannin, A., Le Mapihan, K., Gmyr, V., Caiazzo, R., Torres, F., Raverdy, V., Bonner, C., D'Herbomez, M., Pigny, P., Noel, C., Kerr‐Conte, J., Pattou, F., Vantyghem, M. C.
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Sprache:eng
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Zusammenfassung:In allogenic islet transplantation (IT), high purity of islet preparations and low contamination by nonislet cells are generally favored. The aim of the present study was to analyze the relation between the purity of transplanted preparations and graft function during 5 years post‐IT. Twenty‐four patients with type 1 diabetes, followed for 5 years after IT, were enrolled. Metabolic parameters and daily insulin requirements were compared between patients who received islet preparations with a mean purity
ISSN:1600-6135
1600-6143
DOI:10.1111/ajt.14514