A versatile platform for adding functional properties to amyloid fibrils
Herein we report the design, synthesis, and testing of prototype members of a family of amyloid-binding molecular tools that can manipulate the fibrils by giving them various new functional properties. Potential applications include manipulating disease-relevant fibrils, developing novel functional...
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Veröffentlicht in: | Organic & biomolecular chemistry 2017-10, Vol.15 (38), p.8023-8027 |
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container_title | Organic & biomolecular chemistry |
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creator | Fontaine, Devon F A Ivancic, Valerie A Reardon, Michael B Lazo, Noel D Jakobsche, Charles E |
description | Herein we report the design, synthesis, and testing of prototype members of a family of amyloid-binding molecular tools that can manipulate the fibrils by giving them various new functional properties. Potential applications include manipulating disease-relevant fibrils, developing novel functional nanomaterials, and studying the molecular details of fibril structures. |
doi_str_mv | 10.1039/c7ob02042b |
format | Article |
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source | Royal Society Of Chemistry Journals; Alma/SFX Local Collection |
title | A versatile platform for adding functional properties to amyloid fibrils |
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