Features and outcomes from a retrospective study of 570 hospitalized Chinese patients with drug-induced liver injury

Features and outcomes from a retrospective study of 570 hospitalized Chinese patients with drug-induced liver injury

To investigate the clinical features and outcomes of hospitalized patients with drug-induced liver injury (DILI). The medical records of hospitalized patients with DILI from January 1997 through July 2016 were reviewed. Five hundred seventy cases were reviewed, of which 381 (66.8%) were female. Four...

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Veröffentlicht in:Clinics and research in hepatology and gastroenterology 2018-02, Vol.42 (1), p.48-56
Hauptverfasser: Pang, Lili, Yang, Wanna, Hou, Fengqin
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Adult
Aged
Aged, 80 and over
Chemical and Drug Induced Liver Injury - diagnosis
Chemical and Drug Induced Liver Injury - drug therapy
China
Female
Hospitalization
Humans
Male
Middle Aged
Retrospective Studies
Severity of Illness Index
Treatment Outcome
Young Adult
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Beschreibung
Zusammenfassung:To investigate the clinical features and outcomes of hospitalized patients with drug-induced liver injury (DILI). The medical records of hospitalized patients with DILI from January 1997 through July 2016 were reviewed. Five hundred seventy cases were reviewed, of which 381 (66.8%) were female. Four hundred fifty-eight cases (80.4%) presented with hepatocellular injury, 53 (9.3%) with cholestatic injury and 59 (10.4%) with mixed injury. Chronicity was more common in cholestatic and mixed injury cases than in hepatocellular cases (P
ISSN:2210-7401
2210-741X
DOI:10.1016/j.clinre.2017.08.003