Cycloartane-type triterpene glycosides anopanins A-C with monoacyldigalactosylglycerols from Anodendron paniculatum

Three cycloartane-type triterpene glycosides (anopanins A–C), together with three known monoacyldigalactosylglycerols gingerglycolipids A–C and (2S)-1-O-palmitoyl-3-O-[α-d-galactopyranosyl-(1→6)-β-d-galactopyranosyl]-sn-glycerol, were isolated from the aerial parts of Anodendron paniculatum collecte...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Phytochemistry (Oxford) 2017-12, Vol.144, p.113-118
Hauptverfasser: Ho, Viet Duc, Hoang, Thi Nhu Hanh, Vo, Quoc Hung, Phan, Van Kiem, Le, Tuan Anh, Pham, Viet Ty, Nguyen, Minh Hien, Kodama, Takeshi, Ito, Takuya, Morita, Hiroyuki, Raal, Ain, Nguyen, Thi Hoai
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Three cycloartane-type triterpene glycosides (anopanins A–C), together with three known monoacyldigalactosylglycerols gingerglycolipids A–C and (2S)-1-O-palmitoyl-3-O-[α-d-galactopyranosyl-(1→6)-β-d-galactopyranosyl]-sn-glycerol, were isolated from the aerial parts of Anodendron paniculatum collected in Viet Nam. The chemical structures of the present compounds were elucidated by means of 1D and 2D NMR and HRESIMS spectroscopy, and by comparing to the reported data in the literature. These compounds did not show significant growth inhibitory activities (IC50 > 100 μg/mL) against the tested cancer cell lines LU-1 (lung adenocarcinoma), KB (epidermoid carcinoma), Hep-G2 (hepatoma cancer), MKN-7 (stomach cancer), and SW-480 (colon adenocarcinoma). [Display omitted] •Three previously undescribed cycloartane-type triterpene glycosides anopanins A–C were isolated.•Four monoacyldigalactosylglycerols gingerglycolipids A–C were isolated.•(2S)-1-O-palmitoyl-3-O-[α-D-galactopyranosyl-(1→6)-β-D-galactopyranosyl]-snglycerol isolated.•The compounds did not show significant activities against cancer cell lines.
ISSN:0031-9422
1873-3700
DOI:10.1016/j.phytochem.2017.09.004