Anti-inflammatory activity of Phyllanthus singampattiyana leaf extract

Abstract We studied the anti-inflammatory activity of a petroleum ether extract of Phyllanthus singampattiana. Sebastine and A.N. Henry leaves, which was tested in Wistar rats with TPA-induced ear inflammation and carrageenan-induced paw edema. Carrageenan-induced paw edema was significantly reduced...

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Veröffentlicht in:	Pharmaceutical biology 2005, Vol.43 (4), p.296-298
Hauptverfasser:	Maridass, M, Victor, B, Benniamin, A, Mannan, M.M, Britto, A.J. de
Format:	Artikel
Sprache:	eng
Schlagworte:	animal models Anti-inflammatory activity beta-sitosterol Biological and medical sciences edema General pharmacology hydrocarbons indigenous species leaf extract leaves Medical sciences medicinal plants petroleum Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Phyllanthus Phyllanthus singampattiyana phytochemicals plant extracts rats supercritical fluid extraction tropical and subtropical crops wild plants β.-sitosterol
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Beschreibung
Zusammenfassung:	Abstract We studied the anti-inflammatory activity of a petroleum ether extract of Phyllanthus singampattiana. Sebastine and A.N. Henry leaves, which was tested in Wistar rats with TPA-induced ear inflammation and carrageenan-induced paw edema. Carrageenan-induced paw edema was significantly reduced at a dose of 100 mg petroleum ether extract (p < 0.05%). From the crude extract, β.-sitosterol was identified and confirmed.
ISSN:	1388-0209 1744-5116
DOI:	10.1080/13880200590951667