Clinical evaluation of the newly formatted lateral‐flow device for invasive pulmonary aspergillosis

Summary The study evaluated the newly formatted Aspergillus‐specific lateral‐flow‐device (LFD), and compared its performance to the original prototype “old” LFD test using BALF samples from 28 patients (14 patients with probable/proven invasive pulmonary aspergillosis [IPA] and 14 patients with no evidence for IPA). A total of 10/14 (71%) of BALF samples from patients with probable/proven IPA resulted positive with the new LFD, including 8/9 with true‐positive and 2/5 with false‐negative results with the old LFD. All 14 samples from patients without IPA resulted negative with the new LFD; specificity of the new LFD was significantly improved compared to the old LFD.