Effect of CPAP on sleep spindles in patients with OSA

•We observed increased spindles number under CPAP treatment in OSA patients.•Increased spindles may be played a regulatory effect on sleep apnea symptoms.•OSA patients must be encouraged to adhere CPAP devices for avoiding complications of this disorder. Consequences of OSAS include excessive daytime sleepiness, divided sleep architecture, impaired neurocognitive performance, and significant psychosocial disruption. In this study we aimed to evaluate sleep spindles changes before and after PAP treatment in patient with OSA. Seventy-three consecutive patients (M/F:61/12) who applied to Sleep Disorders Center of Inonu University Hospital and met the inclusion criteria were enrolled to this study. Full-night polysomnography and CPAP titration were performed. Mean AHI were detected as 43,8±24,4 and mean oxygen saturation was 79% in patients under full-night PSG. Singificant increasing were observed on spindle count under CPAP titration (192±98.vs 347±165 per hour p