The impact of obesity and timely antiviral administration on severe influenza outcomes among hospitalized adults

The impact of obesity and timely antiviral administration on severe influenza outcomes among hospitalized adults

Obesity was identified as a risk factor for severe influenza during the 2009 influenza A(H1N1)pandemic, but evidence of this association has been mixed since. Post‐pandemic antiviral treatment guidelines may have increased antiviral treatment among obese individuals. A prospective study of adults ho...

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Veröffentlicht in:Journal of medical virology 2018-02, Vol.90 (2), p.212-218
Hauptverfasser: Segaloff, Hannah E., Evans, Richard, Arshad, Samia, Zervos, Marcus J., Archer, Carolyn, Kaye, Keith S., Martin, Emily T.
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Adults
Aged
Aged, 80 and over
Antiviral agents
Antiviral Agents - administration & dosage
Body mass
Cough
epidemiology
Female
Hospitalization
Humans
Influenza
Influenza A
influenza virus
Influenza, Human - complications
Influenza, Human - drug therapy
Influenza, Human - pathology
Length of Stay
Male
Michigan
Middle Aged
neuraminidase inhibitor
Obesity
Obesity - complications
Pandemics
Patients
Pneumonia - epidemiology
Pneumonia - pathology
Prospective Studies
Regression analysis
Respiratory tract
Respiratory tract diseases
Risk factors
Statistical analysis
Steroid hormones
Steroids
Time Factors
Treatment Outcome
Virology
Young Adult
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Zusammenfassung:Obesity was identified as a risk factor for severe influenza during the 2009 influenza A(H1N1)pandemic, but evidence of this association has been mixed since. Post‐pandemic antiviral treatment guidelines may have increased antiviral treatment among obese individuals. A prospective study of adults hospitalized with laboratory‐confirmed influenza in Detroit, Michigan in 2011‐2012 and 2012‐2013 was conducted. Patient information was collected from interviews and medical chart ion. Obese (BMI ≥ 30) and non‐obese (BMI 2 days from symptom onset), obesity (30 ≤ BMI 
ISSN:0146-6615
1096-9071
DOI:10.1002/jmv.24946