Study of the sleep quality and psychological state of patients with hepatitis B liver cirrhosis

Aim We aimed to investigate sleep quality, mild hepatic encephalopathy, anxiety, and depression in patients with hepatitis B cirrhosis by using a variety of scales and questionnaires. Method A cohort of 341 patients with hepatitis B liver cirrhosis were categorized by Child–Pugh grading (A, B, and C) in this cross‐sectional study. Pittsburgh Sleep Quality Index (PSQI), Number Connection Test‐A (NCT‐A), and Hospital Anxiety and Depression (HAD) evaluated the questionnaires and statistically analyzed the intrinsic correlation. The control group included 50 healthy individuals. Of 341 patients, 213 had a PSQI index >5 points. Results The PSQI, NCT‐A, anxiety scale (HAD [a]), and depression scale (HAD [d]) of the patients were significantly different. The NCT‐A‐positive patients revealed 214 cases of possible minimal hepatic encephalopathy (MHE) during a preliminary screening of patients. The PSQI score of NCT‐A‐positive patients was significantly elevated compared to NCT‐A‐negative patients (P