Synthesis of Functionalized Quinolines through a Reaction of Amides and Alkynes Promoted by Triflic Anhydride/Pyridine

A concise, novel and flexible metal‐free single step to synthesize functionalized quinolines is reported. Triflic anhydride‐mediated (Tf2O) activation of amides is discussed in the presence of pyridine to offer strong electrophiles, thereby showcasing excellent productivity, high regio‐ and chemosel...

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Veröffentlicht in:	Chemistry : a European journal 2017-11, Vol.23 (61), p.15300-15304
Hauptverfasser:	Li, Lian‐Hua, Niu, Zhi‐Jie, Liang, Yong‐Min
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkynes Amides Chemical synthesis Chemistry metal-free Organic compounds Pyridines quinoline Quinolines regioselectivity Substrates synthesis triflic anhydride
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