Synthesis and neuroprotective effects of serofendic acid analogues
Analogues of serofendic acid were prepared and their protective effects against l-glutamate (Glu)-induced neurotoxicity were examined using primary cultures of rat cortical neurons. Analogues of serofendic acid were prepared and their protective effects against l-glutamate (Glu)-induced neurotoxicit...
Gespeichert in:
| Veröffentlicht in: | Bioorganic & medicinal chemistry letters 2006-10, Vol.16 (19), p.5080-5083 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 5083 |
|---|---|
| container_issue | 19 |
| container_start_page | 5080 |
| container_title | Bioorganic & medicinal chemistry letters |
| container_volume | 16 |
| creator | Terauchi, Taro Doko, Takashi Yonaga, Masahiro Kajiwara, Akiharu Niidome, Tetsuhiro Taguchi, Ryota Kume, Toshiaki Akaike, Akinori Sugimoto, Hachiro |
| description | Analogues of serofendic acid were prepared and their protective effects against
l-glutamate (Glu)-induced neurotoxicity were examined using primary cultures of rat cortical neurons.
Analogues of serofendic acid were prepared and their protective effects against
l-glutamate (Glu)-induced neurotoxicity were examined using primary cultures of rat cortical neurons. Some analogues exhibited similar neuroprotective activity to that of serofendic acid. |
| doi_str_mv | 10.1016/j.bmcl.2006.07.038 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_19373836</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0960894X06008146</els_id><sourcerecordid>19373836</sourcerecordid><originalsourceid>FETCH-LOGICAL-c415t-68b40cbc56de5540fef559ed4ae1b7902cb00bcecd41f4e27d2c934f043f4b5d3</originalsourceid><addsrcrecordid>eNp9kE1LxDAQhoMouq7-AQ_Si95aJ22atuBFF79A8KCCt5BOJpql265JV_Dfm2UX9uZp5vDMOy8PY2ccMg5cXs2zdoFdlgPIDKoMinqPTbiQIi0ElPtsAo2EtG7ExxE7DmEOwAUIcciOuGxAFLyZsNvX3378ouBConuT9LTyw9IPI-Hofigha-MWksEmgfxgqTcOE43ORFx3w-eKwgk7sLoLdLqdU_Z-f_c2e0yfXx6eZjfPKQpejqmsWwHYYikNlaUAS7YsGzJCE2-rBnJsAVokNIJbQXllcmwKYWNRK9rSFFN2ucmN_b7j31EtXEDqOt3TsAqKN0VV1IWMYL4B0Q8heLJq6d1C-1_FQa3Nqblam1NrcwoqFc3Fo_Nt-qpdkNmdbFVF4GIL6IC6s1736MKOq0FKWa2DrjccRRc_jrwK6KhHMs5Hl8oM7r8efyczjWQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>19373836</pqid></control><display><type>article</type><title>Synthesis and neuroprotective effects of serofendic acid analogues</title><source>MEDLINE</source><source>ScienceDirect Journals (5 years ago - present)</source><creator>Terauchi, Taro ; Doko, Takashi ; Yonaga, Masahiro ; Kajiwara, Akiharu ; Niidome, Tetsuhiro ; Taguchi, Ryota ; Kume, Toshiaki ; Akaike, Akinori ; Sugimoto, Hachiro</creator><creatorcontrib>Terauchi, Taro ; Doko, Takashi ; Yonaga, Masahiro ; Kajiwara, Akiharu ; Niidome, Tetsuhiro ; Taguchi, Ryota ; Kume, Toshiaki ; Akaike, Akinori ; Sugimoto, Hachiro</creatorcontrib><description>Analogues of serofendic acid were prepared and their protective effects against
l-glutamate (Glu)-induced neurotoxicity were examined using primary cultures of rat cortical neurons.
Analogues of serofendic acid were prepared and their protective effects against
l-glutamate (Glu)-induced neurotoxicity were examined using primary cultures of rat cortical neurons. Some analogues exhibited similar neuroprotective activity to that of serofendic acid.</description><identifier>ISSN: 0960-894X</identifier><identifier>EISSN: 1464-3405</identifier><identifier>DOI: 10.1016/j.bmcl.2006.07.038</identifier><identifier>PMID: 16904319</identifier><language>eng</language><publisher>Oxford: Elsevier Ltd</publisher><subject>Animals ; Atisane ; Biological and medical sciences ; Cells, Cultured ; Diterpenes - chemical synthesis ; Diterpenes - pharmacology ; Glutamate ; Glutamic Acid - adverse effects ; Medical sciences ; Neurons - drug effects ; Neuropharmacology ; Neuroprotective ; Neuroprotective agent ; Neuroprotective Agents - chemical synthesis ; Neurotoxicity Syndromes - drug therapy ; Neurotoxicity Syndromes - pathology ; Neurotoxicity Syndromes - prevention & control ; Pharmacology. Drug treatments ; Rats ; Serofendic acid ; Structure-Activity Relationship</subject><ispartof>Bioorganic & medicinal chemistry letters, 2006-10, Vol.16 (19), p.5080-5083</ispartof><rights>2006 Elsevier Ltd</rights><rights>2007 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c415t-68b40cbc56de5540fef559ed4ae1b7902cb00bcecd41f4e27d2c934f043f4b5d3</citedby><cites>FETCH-LOGICAL-c415t-68b40cbc56de5540fef559ed4ae1b7902cb00bcecd41f4e27d2c934f043f4b5d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.bmcl.2006.07.038$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3548,27923,27924,45994</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=18066678$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16904319$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Terauchi, Taro</creatorcontrib><creatorcontrib>Doko, Takashi</creatorcontrib><creatorcontrib>Yonaga, Masahiro</creatorcontrib><creatorcontrib>Kajiwara, Akiharu</creatorcontrib><creatorcontrib>Niidome, Tetsuhiro</creatorcontrib><creatorcontrib>Taguchi, Ryota</creatorcontrib><creatorcontrib>Kume, Toshiaki</creatorcontrib><creatorcontrib>Akaike, Akinori</creatorcontrib><creatorcontrib>Sugimoto, Hachiro</creatorcontrib><title>Synthesis and neuroprotective effects of serofendic acid analogues</title><title>Bioorganic & medicinal chemistry letters</title><addtitle>Bioorg Med Chem Lett</addtitle><description>Analogues of serofendic acid were prepared and their protective effects against
l-glutamate (Glu)-induced neurotoxicity were examined using primary cultures of rat cortical neurons.
Analogues of serofendic acid were prepared and their protective effects against
l-glutamate (Glu)-induced neurotoxicity were examined using primary cultures of rat cortical neurons. Some analogues exhibited similar neuroprotective activity to that of serofendic acid.</description><subject>Animals</subject><subject>Atisane</subject><subject>Biological and medical sciences</subject><subject>Cells, Cultured</subject><subject>Diterpenes - chemical synthesis</subject><subject>Diterpenes - pharmacology</subject><subject>Glutamate</subject><subject>Glutamic Acid - adverse effects</subject><subject>Medical sciences</subject><subject>Neurons - drug effects</subject><subject>Neuropharmacology</subject><subject>Neuroprotective</subject><subject>Neuroprotective agent</subject><subject>Neuroprotective Agents - chemical synthesis</subject><subject>Neurotoxicity Syndromes - drug therapy</subject><subject>Neurotoxicity Syndromes - pathology</subject><subject>Neurotoxicity Syndromes - prevention & control</subject><subject>Pharmacology. Drug treatments</subject><subject>Rats</subject><subject>Serofendic acid</subject><subject>Structure-Activity Relationship</subject><issn>0960-894X</issn><issn>1464-3405</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1LxDAQhoMouq7-AQ_Si95aJ22atuBFF79A8KCCt5BOJpql265JV_Dfm2UX9uZp5vDMOy8PY2ccMg5cXs2zdoFdlgPIDKoMinqPTbiQIi0ElPtsAo2EtG7ExxE7DmEOwAUIcciOuGxAFLyZsNvX3378ouBConuT9LTyw9IPI-Hofigha-MWksEmgfxgqTcOE43ORFx3w-eKwgk7sLoLdLqdU_Z-f_c2e0yfXx6eZjfPKQpejqmsWwHYYikNlaUAS7YsGzJCE2-rBnJsAVokNIJbQXllcmwKYWNRK9rSFFN2ucmN_b7j31EtXEDqOt3TsAqKN0VV1IWMYL4B0Q8heLJq6d1C-1_FQa3Nqblam1NrcwoqFc3Fo_Nt-qpdkNmdbFVF4GIL6IC6s1736MKOq0FKWa2DrjccRRc_jrwK6KhHMs5Hl8oM7r8efyczjWQ</recordid><startdate>20061001</startdate><enddate>20061001</enddate><creator>Terauchi, Taro</creator><creator>Doko, Takashi</creator><creator>Yonaga, Masahiro</creator><creator>Kajiwara, Akiharu</creator><creator>Niidome, Tetsuhiro</creator><creator>Taguchi, Ryota</creator><creator>Kume, Toshiaki</creator><creator>Akaike, Akinori</creator><creator>Sugimoto, Hachiro</creator><general>Elsevier Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>7TK</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope></search><sort><creationdate>20061001</creationdate><title>Synthesis and neuroprotective effects of serofendic acid analogues</title><author>Terauchi, Taro ; Doko, Takashi ; Yonaga, Masahiro ; Kajiwara, Akiharu ; Niidome, Tetsuhiro ; Taguchi, Ryota ; Kume, Toshiaki ; Akaike, Akinori ; Sugimoto, Hachiro</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c415t-68b40cbc56de5540fef559ed4ae1b7902cb00bcecd41f4e27d2c934f043f4b5d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Animals</topic><topic>Atisane</topic><topic>Biological and medical sciences</topic><topic>Cells, Cultured</topic><topic>Diterpenes - chemical synthesis</topic><topic>Diterpenes - pharmacology</topic><topic>Glutamate</topic><topic>Glutamic Acid - adverse effects</topic><topic>Medical sciences</topic><topic>Neurons - drug effects</topic><topic>Neuropharmacology</topic><topic>Neuroprotective</topic><topic>Neuroprotective agent</topic><topic>Neuroprotective Agents - chemical synthesis</topic><topic>Neurotoxicity Syndromes - drug therapy</topic><topic>Neurotoxicity Syndromes - pathology</topic><topic>Neurotoxicity Syndromes - prevention & control</topic><topic>Pharmacology. Drug treatments</topic><topic>Rats</topic><topic>Serofendic acid</topic><topic>Structure-Activity Relationship</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Terauchi, Taro</creatorcontrib><creatorcontrib>Doko, Takashi</creatorcontrib><creatorcontrib>Yonaga, Masahiro</creatorcontrib><creatorcontrib>Kajiwara, Akiharu</creatorcontrib><creatorcontrib>Niidome, Tetsuhiro</creatorcontrib><creatorcontrib>Taguchi, Ryota</creatorcontrib><creatorcontrib>Kume, Toshiaki</creatorcontrib><creatorcontrib>Akaike, Akinori</creatorcontrib><creatorcontrib>Sugimoto, Hachiro</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><jtitle>Bioorganic & medicinal chemistry letters</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Terauchi, Taro</au><au>Doko, Takashi</au><au>Yonaga, Masahiro</au><au>Kajiwara, Akiharu</au><au>Niidome, Tetsuhiro</au><au>Taguchi, Ryota</au><au>Kume, Toshiaki</au><au>Akaike, Akinori</au><au>Sugimoto, Hachiro</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Synthesis and neuroprotective effects of serofendic acid analogues</atitle><jtitle>Bioorganic & medicinal chemistry letters</jtitle><addtitle>Bioorg Med Chem Lett</addtitle><date>2006-10-01</date><risdate>2006</risdate><volume>16</volume><issue>19</issue><spage>5080</spage><epage>5083</epage><pages>5080-5083</pages><issn>0960-894X</issn><eissn>1464-3405</eissn><abstract>Analogues of serofendic acid were prepared and their protective effects against
l-glutamate (Glu)-induced neurotoxicity were examined using primary cultures of rat cortical neurons.
Analogues of serofendic acid were prepared and their protective effects against
l-glutamate (Glu)-induced neurotoxicity were examined using primary cultures of rat cortical neurons. Some analogues exhibited similar neuroprotective activity to that of serofendic acid.</abstract><cop>Oxford</cop><pub>Elsevier Ltd</pub><pmid>16904319</pmid><doi>10.1016/j.bmcl.2006.07.038</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0960-894X |
| ispartof | Bioorganic & medicinal chemistry letters, 2006-10, Vol.16 (19), p.5080-5083 |
| issn | 0960-894X 1464-3405 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_19373836 |
| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | Animals Atisane Biological and medical sciences Cells, Cultured Diterpenes - chemical synthesis Diterpenes - pharmacology Glutamate Glutamic Acid - adverse effects Medical sciences Neurons - drug effects Neuropharmacology Neuroprotective Neuroprotective agent Neuroprotective Agents - chemical synthesis Neurotoxicity Syndromes - drug therapy Neurotoxicity Syndromes - pathology Neurotoxicity Syndromes - prevention & control Pharmacology. Drug treatments Rats Serofendic acid Structure-Activity Relationship |
| title | Synthesis and neuroprotective effects of serofendic acid analogues |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-11T23%3A19%3A05IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Synthesis%20and%20neuroprotective%20effects%20of%20serofendic%20acid%20analogues&rft.jtitle=Bioorganic%20&%20medicinal%20chemistry%20letters&rft.au=Terauchi,%20Taro&rft.date=2006-10-01&rft.volume=16&rft.issue=19&rft.spage=5080&rft.epage=5083&rft.pages=5080-5083&rft.issn=0960-894X&rft.eissn=1464-3405&rft_id=info:doi/10.1016/j.bmcl.2006.07.038&rft_dat=%3Cproquest_cross%3E19373836%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=19373836&rft_id=info:pmid/16904319&rft_els_id=S0960894X06008146&rfr_iscdi=true |