Precision Diagnosis and Treatment for Advanced Non–Small-Cell Lung Cancer

Smoking cessation has reduced the incidence of lung cancer. The authors of this review discuss recent progress in diagnostic and treatment approaches, including molecular characterization to determine the likelihood of a response to targeted agents and immunotherapies.

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Bibliographische Detailangaben
Veröffentlicht in:	The New England journal of medicine 2017-08, Vol.377 (9), p.849-861
Hauptverfasser:	Reck, Martin, Rabe, Klaus F
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Antineoplastic Agents - therapeutic use Bronchoscopy - methods Cancer therapies Carcinoma, Non-Small-Cell Lung - diagnosis Carcinoma, Non-Small-Cell Lung - drug therapy Carcinoma, Non-Small-Cell Lung - genetics Carcinoma, Non-Small-Cell Lung - pathology Chemotherapy Classification Diagnosis Endoscopy Epidermal growth factor Esophagus Genes, erbB-1 Humans Immunotherapy Ligands Lung cancer Lung Neoplasms - diagnosis Lung Neoplasms - drug therapy Lung Neoplasms - genetics Lung Neoplasms - pathology Lymphatic system Medical diagnosis Medical imaging Medical prognosis Metastasis Mortality Mutation Neoplasm Staging NMR Nuclear magnetic resonance Tobacco Tomography Tumors Ultrasonic imaging Ultrasonography
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Beschreibung
Zusammenfassung:	Smoking cessation has reduced the incidence of lung cancer. The authors of this review discuss recent progress in diagnostic and treatment approaches, including molecular characterization to determine the likelihood of a response to targeted agents and immunotherapies.
ISSN:	0028-4793 1533-4406
DOI:	10.1056/NEJMra1703413