Frequency and clinical significance of chromosome 7 and 10 aneuploidies, amplification of the EGFR gene, deletion of PTEN and TP53 genes, and 1p/19q deficiency in a sample of adult patients diagnosed with glioblastoma from Southern Brazil

Glioblastoma stands out as the most frequent central nervous system neoplasia, presenting a poor prognosis. The aim of this study was to verify the frequency and clinical significance of the aneuploidy of chromosomes 7 and 10, EGFR amplification, PTEN and TP53 deletions and 1p/19q deficiency in adul...

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Veröffentlicht in:Journal of neuro-oncology 2017-12, Vol.135 (3), p.465-472
Hauptverfasser: Koshiyama, Dayane B., Trevisan, Patrícia, Graziadio, Carla, Rosa, Rafael F. M., Cunegatto, Bibiana, Scholl, Juliete, Provenzi, Valentina O., de Sá, Alexandre P., Soares, Fabiano P., Velho, Maíra C., de A. P. Filho, Nelson, Oliveira, Ceres A., Zen, Paulo R. G.
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Sprache:eng
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