A Preliminary Evaluation of Ovine Bladder Mucosal Damage Associated With 2 Different Indwelling Urinary Catheters
To determine whether a new catheter design with a low-profile, open-ended rounded rather than pointed Foley catheter tip can reduce mucosal damage to the bladder of ewes. Six ewes were randomly assigned to 1 of 2 indwelling urinary catheters—a 16 Fr Foley catheter or a 16 Fr open-tip CystoSure cathe...
Gespeichert in:
| Veröffentlicht in: | Urology (Ridgewood, N.J.) N.J.), 2017-12, Vol.110, p.248-252 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 252 |
|---|---|
| container_issue | |
| container_start_page | 248 |
| container_title | Urology (Ridgewood, N.J.) |
| container_volume | 110 |
| creator | Greenberg, James A. Grazul-Bilska, Anna T. Webb, Brett T. Sun, Xin Vonnahme, Kimberly A. |
| description | To determine whether a new catheter design with a low-profile, open-ended rounded rather than pointed Foley catheter tip can reduce mucosal damage to the bladder of ewes.
Six ewes were randomly assigned to 1 of 2 indwelling urinary catheters—a 16 Fr Foley catheter or a 16 Fr open-tip CystoSure catheter. After 96 hours, all the animals were sacrificed and their bladder and urethra harvested for analysis.
Image analysis of the bladder surfaces demonstrated a significant decrease in the percentage of bladder area covered by ulceration and inflammation in sheep with CystoSure catheters compared with Foley catheters (P |
| doi_str_mv | 10.1016/j.urology.2017.08.020 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1933606537</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0090429517308816</els_id><sourcerecordid>1933606537</sourcerecordid><originalsourceid>FETCH-LOGICAL-c365t-37c074881ac6a6f22cf0498d49b88e28d34e902783b7aaae41aeab3fc92121633</originalsourceid><addsrcrecordid>eNqFkMtu1DAUhi0EokPhEUBeskk4thNfVmiYFqhUVBZULC2PczL1KIlb25mqb0-qGdiyOpv_dj5C3jOoGTD5aV_PKQ5x91RzYKoGXQOHF2TFWq4qY0z7kqwADFQNN-0ZeZPzHgCklOo1OeNaN0pqtSIPa_oz4RDGMLn0RC8PbphdCXGisac3hzAh_TK4rsNEf8w-ZjfQCze6HdJ1ztEHV7Cjv0O5o5xehL7HhFOhV1P3iMMQph29TcfkjSt3WDDlt-RV74aM7073nNx-vfy1-V5d33y72qyvKy9kWyqhPKhGa-a8dLLn3PfQGN01Zqs1ct2JBg1wpcVWOeewYQ7dVvTecMaZFOKcfDzm3qf4MGMudgzZL6vchHHOlhkhJMhWqEXaHqU-xZwT9vY-hXFZbRnYZ9p2b0-07TNtC9outBffh1PFvB2x--f6i3cRfD4KcHn0EDDZ7ANOHruQ0BfbxfCfij9w0pRU</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1933606537</pqid></control><display><type>article</type><title>A Preliminary Evaluation of Ovine Bladder Mucosal Damage Associated With 2 Different Indwelling Urinary Catheters</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Greenberg, James A. ; Grazul-Bilska, Anna T. ; Webb, Brett T. ; Sun, Xin ; Vonnahme, Kimberly A.</creator><creatorcontrib>Greenberg, James A. ; Grazul-Bilska, Anna T. ; Webb, Brett T. ; Sun, Xin ; Vonnahme, Kimberly A.</creatorcontrib><description>To determine whether a new catheter design with a low-profile, open-ended rounded rather than pointed Foley catheter tip can reduce mucosal damage to the bladder of ewes.
Six ewes were randomly assigned to 1 of 2 indwelling urinary catheters—a 16 Fr Foley catheter or a 16 Fr open-tip CystoSure catheter. After 96 hours, all the animals were sacrificed and their bladder and urethra harvested for analysis.
Image analysis of the bladder surfaces demonstrated a significant decrease in the percentage of bladder area covered by ulceration and inflammation in sheep with CystoSure catheters compared with Foley catheters (P < .002) as well as a trend toward less edema (P = .17). Macro-morphologic evaluations were confirmed with immunohistochemical markers of cell proliferation and inflammation.
In this pilot study, we were able to demonstrate that a new catheter design with an open-ended rounded rather than pointed tip and a reduced balloon base-to-tip profile may reduce mucosal damage to the bladder of ewes. Based on the findings from this trial, we believe this new catheter design with its low-profile, rounded tip may reduce bladder mucosal injury, which is a risk factor for catheter-associated urinary tract infections.</description><identifier>ISSN: 0090-4295</identifier><identifier>EISSN: 1527-9995</identifier><identifier>DOI: 10.1016/j.urology.2017.08.020</identifier><identifier>PMID: 28847687</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Animals ; Catheters, Indwelling - adverse effects ; Equipment Design ; Female ; Mucous Membrane - pathology ; Pilot Projects ; Random Allocation ; Sheep ; Urethra - pathology ; Urinary Bladder - pathology ; Urinary Bladder Diseases - etiology ; Urinary Catheters - adverse effects</subject><ispartof>Urology (Ridgewood, N.J.), 2017-12, Vol.110, p.248-252</ispartof><rights>2017 Elsevier Inc.</rights><rights>Copyright © 2017 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c365t-37c074881ac6a6f22cf0498d49b88e28d34e902783b7aaae41aeab3fc92121633</citedby><cites>FETCH-LOGICAL-c365t-37c074881ac6a6f22cf0498d49b88e28d34e902783b7aaae41aeab3fc92121633</cites><orcidid>0000-0002-6783-6078</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0090429517308816$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28847687$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Greenberg, James A.</creatorcontrib><creatorcontrib>Grazul-Bilska, Anna T.</creatorcontrib><creatorcontrib>Webb, Brett T.</creatorcontrib><creatorcontrib>Sun, Xin</creatorcontrib><creatorcontrib>Vonnahme, Kimberly A.</creatorcontrib><title>A Preliminary Evaluation of Ovine Bladder Mucosal Damage Associated With 2 Different Indwelling Urinary Catheters</title><title>Urology (Ridgewood, N.J.)</title><addtitle>Urology</addtitle><description>To determine whether a new catheter design with a low-profile, open-ended rounded rather than pointed Foley catheter tip can reduce mucosal damage to the bladder of ewes.
Six ewes were randomly assigned to 1 of 2 indwelling urinary catheters—a 16 Fr Foley catheter or a 16 Fr open-tip CystoSure catheter. After 96 hours, all the animals were sacrificed and their bladder and urethra harvested for analysis.
Image analysis of the bladder surfaces demonstrated a significant decrease in the percentage of bladder area covered by ulceration and inflammation in sheep with CystoSure catheters compared with Foley catheters (P < .002) as well as a trend toward less edema (P = .17). Macro-morphologic evaluations were confirmed with immunohistochemical markers of cell proliferation and inflammation.
In this pilot study, we were able to demonstrate that a new catheter design with an open-ended rounded rather than pointed tip and a reduced balloon base-to-tip profile may reduce mucosal damage to the bladder of ewes. Based on the findings from this trial, we believe this new catheter design with its low-profile, rounded tip may reduce bladder mucosal injury, which is a risk factor for catheter-associated urinary tract infections.</description><subject>Animals</subject><subject>Catheters, Indwelling - adverse effects</subject><subject>Equipment Design</subject><subject>Female</subject><subject>Mucous Membrane - pathology</subject><subject>Pilot Projects</subject><subject>Random Allocation</subject><subject>Sheep</subject><subject>Urethra - pathology</subject><subject>Urinary Bladder - pathology</subject><subject>Urinary Bladder Diseases - etiology</subject><subject>Urinary Catheters - adverse effects</subject><issn>0090-4295</issn><issn>1527-9995</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkMtu1DAUhi0EokPhEUBeskk4thNfVmiYFqhUVBZULC2PczL1KIlb25mqb0-qGdiyOpv_dj5C3jOoGTD5aV_PKQ5x91RzYKoGXQOHF2TFWq4qY0z7kqwADFQNN-0ZeZPzHgCklOo1OeNaN0pqtSIPa_oz4RDGMLn0RC8PbphdCXGisac3hzAh_TK4rsNEf8w-ZjfQCze6HdJ1ztEHV7Cjv0O5o5xehL7HhFOhV1P3iMMQph29TcfkjSt3WDDlt-RV74aM7073nNx-vfy1-V5d33y72qyvKy9kWyqhPKhGa-a8dLLn3PfQGN01Zqs1ct2JBg1wpcVWOeewYQ7dVvTecMaZFOKcfDzm3qf4MGMudgzZL6vchHHOlhkhJMhWqEXaHqU-xZwT9vY-hXFZbRnYZ9p2b0-07TNtC9outBffh1PFvB2x--f6i3cRfD4KcHn0EDDZ7ANOHruQ0BfbxfCfij9w0pRU</recordid><startdate>201712</startdate><enddate>201712</enddate><creator>Greenberg, James A.</creator><creator>Grazul-Bilska, Anna T.</creator><creator>Webb, Brett T.</creator><creator>Sun, Xin</creator><creator>Vonnahme, Kimberly A.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-6783-6078</orcidid></search><sort><creationdate>201712</creationdate><title>A Preliminary Evaluation of Ovine Bladder Mucosal Damage Associated With 2 Different Indwelling Urinary Catheters</title><author>Greenberg, James A. ; Grazul-Bilska, Anna T. ; Webb, Brett T. ; Sun, Xin ; Vonnahme, Kimberly A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c365t-37c074881ac6a6f22cf0498d49b88e28d34e902783b7aaae41aeab3fc92121633</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Animals</topic><topic>Catheters, Indwelling - adverse effects</topic><topic>Equipment Design</topic><topic>Female</topic><topic>Mucous Membrane - pathology</topic><topic>Pilot Projects</topic><topic>Random Allocation</topic><topic>Sheep</topic><topic>Urethra - pathology</topic><topic>Urinary Bladder - pathology</topic><topic>Urinary Bladder Diseases - etiology</topic><topic>Urinary Catheters - adverse effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Greenberg, James A.</creatorcontrib><creatorcontrib>Grazul-Bilska, Anna T.</creatorcontrib><creatorcontrib>Webb, Brett T.</creatorcontrib><creatorcontrib>Sun, Xin</creatorcontrib><creatorcontrib>Vonnahme, Kimberly A.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Urology (Ridgewood, N.J.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Greenberg, James A.</au><au>Grazul-Bilska, Anna T.</au><au>Webb, Brett T.</au><au>Sun, Xin</au><au>Vonnahme, Kimberly A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Preliminary Evaluation of Ovine Bladder Mucosal Damage Associated With 2 Different Indwelling Urinary Catheters</atitle><jtitle>Urology (Ridgewood, N.J.)</jtitle><addtitle>Urology</addtitle><date>2017-12</date><risdate>2017</risdate><volume>110</volume><spage>248</spage><epage>252</epage><pages>248-252</pages><issn>0090-4295</issn><eissn>1527-9995</eissn><abstract>To determine whether a new catheter design with a low-profile, open-ended rounded rather than pointed Foley catheter tip can reduce mucosal damage to the bladder of ewes.
Six ewes were randomly assigned to 1 of 2 indwelling urinary catheters—a 16 Fr Foley catheter or a 16 Fr open-tip CystoSure catheter. After 96 hours, all the animals were sacrificed and their bladder and urethra harvested for analysis.
Image analysis of the bladder surfaces demonstrated a significant decrease in the percentage of bladder area covered by ulceration and inflammation in sheep with CystoSure catheters compared with Foley catheters (P < .002) as well as a trend toward less edema (P = .17). Macro-morphologic evaluations were confirmed with immunohistochemical markers of cell proliferation and inflammation.
In this pilot study, we were able to demonstrate that a new catheter design with an open-ended rounded rather than pointed tip and a reduced balloon base-to-tip profile may reduce mucosal damage to the bladder of ewes. Based on the findings from this trial, we believe this new catheter design with its low-profile, rounded tip may reduce bladder mucosal injury, which is a risk factor for catheter-associated urinary tract infections.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>28847687</pmid><doi>10.1016/j.urology.2017.08.020</doi><tpages>5</tpages><orcidid>https://orcid.org/0000-0002-6783-6078</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0090-4295 |
| ispartof | Urology (Ridgewood, N.J.), 2017-12, Vol.110, p.248-252 |
| issn | 0090-4295 1527-9995 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1933606537 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Animals Catheters, Indwelling - adverse effects Equipment Design Female Mucous Membrane - pathology Pilot Projects Random Allocation Sheep Urethra - pathology Urinary Bladder - pathology Urinary Bladder Diseases - etiology Urinary Catheters - adverse effects |
| title | A Preliminary Evaluation of Ovine Bladder Mucosal Damage Associated With 2 Different Indwelling Urinary Catheters |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-10T15%3A16%3A12IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20Preliminary%20Evaluation%20of%20Ovine%20Bladder%20Mucosal%20Damage%20Associated%20With%202%20Different%20Indwelling%20Urinary%20Catheters&rft.jtitle=Urology%20(Ridgewood,%20N.J.)&rft.au=Greenberg,%20James%20A.&rft.date=2017-12&rft.volume=110&rft.spage=248&rft.epage=252&rft.pages=248-252&rft.issn=0090-4295&rft.eissn=1527-9995&rft_id=info:doi/10.1016/j.urology.2017.08.020&rft_dat=%3Cproquest_cross%3E1933606537%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1933606537&rft_id=info:pmid/28847687&rft_els_id=S0090429517308816&rfr_iscdi=true |