HLA gene and haplotype frequencies in a Nagaybaks population from the Chelyabinsk Region (Russian South Urals)

A total of 112 Nagaybaks, a Turkic ethnoconfessional group living mainly in the Nagaybak district of the Chelyabinsk Region of Russian South Urals, were genotyped for HLA-A, -B, -DRB1, -DQA1 and -DQB1 loci using PCR-SSP (low-resolution) and HLA-A29 (high-resolution). All loci were in Hardy-Weinberg...

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Veröffentlicht in:Human immunology 2017-10, Vol.78 (10), p.595-601
Hauptverfasser: Suslova, T.A., Burmistrova, A.L., Vavilov, M.N., Chernova, M.S, Khromova, E.B., Belyaeva, S.V., Zaripova, O.N., Stashkevich, D.S., Galkin, A.S., Darke, C.
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Sprache:eng
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Zusammenfassung:A total of 112 Nagaybaks, a Turkic ethnoconfessional group living mainly in the Nagaybak district of the Chelyabinsk Region of Russian South Urals, were genotyped for HLA-A, -B, -DRB1, -DQA1 and -DQB1 loci using PCR-SSP (low-resolution) and HLA-A29 (high-resolution). All loci were in Hardy-Weinberg equilibrium (all p values >0.1 thus showing no locus-level deviations. The genotype data are available in the Allele Frequencies Net Database under the population name ‘‘Russia, South Ural, Chelyabinsk Region, Nagaybaks” and the identifier AFND0003397.
ISSN:0198-8859
1879-1166
DOI:10.1016/j.humimm.2017.08.005