Low cerebral blood flow after cardiac arrest is not associated with anaerobic cerebral metabolism

Estimation of cerebral anaerobic metabolism in survivors and non-survivors after cardiac arrest. We performed an observational study in twenty comatose patients after cardiac arrest and 19 healthy control subjects. We measured mean flow velocity in the middle cerebral artery (MFVMCA) by transcranial...

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Veröffentlicht in:	Resuscitation 2017-11, Vol.120, p.45-50
Hauptverfasser:	Hoedemaekers, Cornelia W., Ainslie, Philip N., Hinssen, Stijn, Aries, Marcel J., Bisschops, Laurens L., Hofmeijer, Jeannette, van der Hoeven, Johannes G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Anaerobiosis Analysis of Variance Cardiac arrest Cardiopulmonary Resuscitation Case-Control Studies Cerebral blood flow Cerebrovascular Circulation Coma - physiopathology Female Humans Hypothermia, Induced Lactate Male Metabolism Middle Aged Middle Cerebral Artery - physiopathology Out-of-Hospital Cardiac Arrest - metabolism Out-of-Hospital Cardiac Arrest - physiopathology Out-of-Hospital Cardiac Arrest - therapy Oxygen - blood Post-cardiac arrest syndrome Prospective Studies
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Zusammenfassung:	Estimation of cerebral anaerobic metabolism in survivors and non-survivors after cardiac arrest. We performed an observational study in twenty comatose patients after cardiac arrest and 19 healthy control subjects. We measured mean flow velocity in the middle cerebral artery (MFVMCA) by transcranial Doppler. Arterial and jugular blood samples were used for calculation of the jugular venous-to-arterial CO2/arterial to-jugular venous O2 content difference ratio. After cardiac arrest, MFVMCA increased from 26.0[18.6–40.4]cm/sec on admission to 63.9[48.3–73.1]cm/sec after 72h (p
ISSN:	0300-9572 1873-1570
DOI:	10.1016/j.resuscitation.2017.08.218