Case–control study of chronic low‐level exposure of inorganic arsenic species and non‐melanoma skin cancer

A significant relationship between arsenic exposure and non‐melanoma skin cancer (NMSC) is well known. The toxicity of arsenics which develop NMSC is dependent on their species. Accordingly, total arsenic levels are unreliable for risk assessment of NMSC. However, there are few studies on quantitati...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of dermatology 2017-12, Vol.44 (12), p.1374-1379
Hauptverfasser:	Kim, Tae‐Hoon, Seo, Jeong‐Wook, Hong, Young‐Seoub, Song, Ki‐Hoon
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Arsenic Arsenic - toxicity Arsenicals - urine basal cell carcinoma Biopsy Case-Control Studies Creatinine Female High-performance liquid chromatography Humans Male Mass spectroscopy Melanoma Middle Aged non‐melanoma skin cancer Risk assessment Skin cancer Skin Neoplasms - chemically induced speciation Species squamous cell carcinoma Toxicity
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	A significant relationship between arsenic exposure and non‐melanoma skin cancer (NMSC) is well known. The toxicity of arsenics which develop NMSC is dependent on their species. Accordingly, total arsenic levels are unreliable for risk assessment of NMSC. However, there are few studies on quantitative exposure assessment of arsenic species in NMSC patients. To validate the contribution of each arsenic species to NMSC, we compared the creatinine‐adjusted urinary concentration of arsenic species in NMSC patients and community controls. A total of 124 biopsy‐proven NMSC cases and 125 age‐ and sex‐matched community controls, drinking tap water with low‐level arsenic concentration (
ISSN:	0385-2407 1346-8138
DOI:	10.1111/1346-8138.13993