Structural Features of Lipopolysaccharide from Rickettsia Typhi: The Causative Agent of Endemic Typhus
: Rickettsia typhi causes endemic typhus, a relatively mild, acute febrile illness characterized by headache and macular rash. It is maintained in rodents and transmitted to humans by flea Xenopsylla cheopis. R. typhi contains a lipopolysaccharide thought to display a noticeable antigenic activity....
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Veröffentlicht in: | Annals of the New York Academy of Sciences 2005-12, Vol.1063 (1), p.259-260 |
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container_title | Annals of the New York Academy of Sciences |
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creator | FODOROVA, MARCELA VADOVIC, PAVOL SKULTETY, LUDOVIT SLABA, KATARINA TOMAN, RUDOLF |
description | : Rickettsia typhi causes endemic typhus, a relatively mild, acute febrile illness characterized by headache and macular rash. It is maintained in rodents and transmitted to humans by flea Xenopsylla cheopis. R. typhi contains a lipopolysaccharide thought to display a noticeable antigenic activity. We examined its structural features and it appears that the O‐specific chain of the R. typhi LPS is composed mainly of the alternating Glc and QuiNAc residues linked by 1→4 bonds. |
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It is maintained in rodents and transmitted to humans by flea Xenopsylla cheopis. R. typhi contains a lipopolysaccharide thought to display a noticeable antigenic activity. 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We examined its structural features and it appears that the O‐specific chain of the R. typhi LPS is composed mainly of the alternating Glc and QuiNAc residues linked by 1→4 bonds.</description><subject>Animals</subject><subject>Carbohydrate Conformation</subject><subject>Carbohydrate Sequence</subject><subject>composition</subject><subject>Electrophoresis, Polyacrylamide Gel</subject><subject>endemic typhus</subject><subject>Gas Chromatography-Mass Spectrometry</subject><subject>Humans</subject><subject>lipopolysaccharide</subject><subject>Lipopolysaccharides - chemistry</subject><subject>Lipopolysaccharides - isolation & purification</subject><subject>Lipopolysaccharides - toxicity</subject><subject>Rickettsia typhi</subject><subject>Rickettsia typhi - chemistry</subject><subject>Rickettsia typhi - immunology</subject><subject>Spectrometry, Mass, Electrospray Ionization</subject><subject>structure</subject><subject>Typhus, Endemic Flea-Borne - metabolism</subject><subject>Typhus, Endemic Flea-Borne - microbiology</subject><subject>Xenopsylla cheopis</subject><issn>0077-8923</issn><issn>1749-6632</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkM1v0zAYhy0EYmXjzA3lxC2dHduxza2q1g2pDGkrIE7WG-cNNcsXdsLof09KKjju5PfwPD9ZDyFvGF0yZvJLaFuo45JxKZdUsGdkwZQwaZ7z7DlZUKpUqk3Gz8irGH9QyjIt1EtyxnKhmczEglT3QxjdMAaokw3CdGBMuirZ-r7ru_oQwbk9BF9iUoWuSe68e8BhiB6S3aHf-_fJbo_JGsYIg_-Fyeo7tsNx4KotsfHuLzXGC_Kimj6Kr0_vOfm8udqtb9Ltp-sP69U2dYIak0ouTZ6BoqaklRZVXuqsdKXMyqKAAqAqAVUhJCqO2oACxwrHlXBU6Vyzip-Td_NuH7qfI8bBNj46rGtosRujZSbT2ggxgZcz6EIXY8DK9sE3EA6WUXtMa-e09pjWTmkn4-1peiwaLP_zp5YTIGbg0dd4eGrP3n5b3WfSTFo6az4O-PufBuHB5oorab_eXlult1825o7aj_wPaqyXoA</recordid><startdate>200512</startdate><enddate>200512</enddate><creator>FODOROVA, MARCELA</creator><creator>VADOVIC, PAVOL</creator><creator>SKULTETY, LUDOVIT</creator><creator>SLABA, KATARINA</creator><creator>TOMAN, RUDOLF</creator><general>Blackwell Publishing Ltd</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>C1K</scope></search><sort><creationdate>200512</creationdate><title>Structural Features of Lipopolysaccharide from Rickettsia Typhi: The Causative Agent of Endemic Typhus</title><author>FODOROVA, MARCELA ; VADOVIC, PAVOL ; SKULTETY, LUDOVIT ; SLABA, KATARINA ; TOMAN, RUDOLF</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4099-535962a709d0f84f6d82dcd52dbbabaafdae7b45e73e89a7ac1bc374c078681f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Animals</topic><topic>Carbohydrate Conformation</topic><topic>Carbohydrate Sequence</topic><topic>composition</topic><topic>Electrophoresis, Polyacrylamide Gel</topic><topic>endemic typhus</topic><topic>Gas Chromatography-Mass Spectrometry</topic><topic>Humans</topic><topic>lipopolysaccharide</topic><topic>Lipopolysaccharides - chemistry</topic><topic>Lipopolysaccharides - isolation & purification</topic><topic>Lipopolysaccharides - toxicity</topic><topic>Rickettsia typhi</topic><topic>Rickettsia typhi - chemistry</topic><topic>Rickettsia typhi - immunology</topic><topic>Spectrometry, Mass, Electrospray Ionization</topic><topic>structure</topic><topic>Typhus, Endemic Flea-Borne - metabolism</topic><topic>Typhus, Endemic Flea-Borne - microbiology</topic><topic>Xenopsylla cheopis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>FODOROVA, MARCELA</creatorcontrib><creatorcontrib>VADOVIC, PAVOL</creatorcontrib><creatorcontrib>SKULTETY, LUDOVIT</creatorcontrib><creatorcontrib>SLABA, KATARINA</creatorcontrib><creatorcontrib>TOMAN, RUDOLF</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Environmental Sciences and Pollution Management</collection><jtitle>Annals of the New York Academy of Sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>FODOROVA, MARCELA</au><au>VADOVIC, PAVOL</au><au>SKULTETY, LUDOVIT</au><au>SLABA, KATARINA</au><au>TOMAN, RUDOLF</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Structural Features of Lipopolysaccharide from Rickettsia Typhi: The Causative Agent of Endemic Typhus</atitle><jtitle>Annals of the New York Academy of Sciences</jtitle><addtitle>Ann N Y Acad Sci</addtitle><date>2005-12</date><risdate>2005</risdate><volume>1063</volume><issue>1</issue><spage>259</spage><epage>260</epage><pages>259-260</pages><issn>0077-8923</issn><eissn>1749-6632</eissn><abstract>: Rickettsia typhi causes endemic typhus, a relatively mild, acute febrile illness characterized by headache and macular rash. 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subjects | Animals Carbohydrate Conformation Carbohydrate Sequence composition Electrophoresis, Polyacrylamide Gel endemic typhus Gas Chromatography-Mass Spectrometry Humans lipopolysaccharide Lipopolysaccharides - chemistry Lipopolysaccharides - isolation & purification Lipopolysaccharides - toxicity Rickettsia typhi Rickettsia typhi - chemistry Rickettsia typhi - immunology Spectrometry, Mass, Electrospray Ionization structure Typhus, Endemic Flea-Borne - metabolism Typhus, Endemic Flea-Borne - microbiology Xenopsylla cheopis |
title | Structural Features of Lipopolysaccharide from Rickettsia Typhi: The Causative Agent of Endemic Typhus |
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