Structural Features of Lipopolysaccharide from Rickettsia Typhi: The Causative Agent of Endemic Typhus

: Rickettsia typhi causes endemic typhus, a relatively mild, acute febrile illness characterized by headache and macular rash. It is maintained in rodents and transmitted to humans by flea Xenopsylla cheopis. R. typhi contains a lipopolysaccharide thought to display a noticeable antigenic activity....

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Veröffentlicht in:Annals of the New York Academy of Sciences 2005-12, Vol.1063 (1), p.259-260
Hauptverfasser: FODOROVA, MARCELA, VADOVIC, PAVOL, SKULTETY, LUDOVIT, SLABA, KATARINA, TOMAN, RUDOLF
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container_title Annals of the New York Academy of Sciences
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creator FODOROVA, MARCELA
VADOVIC, PAVOL
SKULTETY, LUDOVIT
SLABA, KATARINA
TOMAN, RUDOLF
description : Rickettsia typhi causes endemic typhus, a relatively mild, acute febrile illness characterized by headache and macular rash. It is maintained in rodents and transmitted to humans by flea Xenopsylla cheopis. R. typhi contains a lipopolysaccharide thought to display a noticeable antigenic activity. We examined its structural features and it appears that the O‐specific chain of the R. typhi LPS is composed mainly of the alternating Glc and QuiNAc residues linked by 1→4 bonds.
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It is maintained in rodents and transmitted to humans by flea Xenopsylla cheopis. R. typhi contains a lipopolysaccharide thought to display a noticeable antigenic activity. 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source MEDLINE; Wiley Online Library Journals Frontfile Complete
subjects Animals
Carbohydrate Conformation
Carbohydrate Sequence
composition
Electrophoresis, Polyacrylamide Gel
endemic typhus
Gas Chromatography-Mass Spectrometry
Humans
lipopolysaccharide
Lipopolysaccharides - chemistry
Lipopolysaccharides - isolation & purification
Lipopolysaccharides - toxicity
Rickettsia typhi
Rickettsia typhi - chemistry
Rickettsia typhi - immunology
Spectrometry, Mass, Electrospray Ionization
structure
Typhus, Endemic Flea-Borne - metabolism
Typhus, Endemic Flea-Borne - microbiology
Xenopsylla cheopis
title Structural Features of Lipopolysaccharide from Rickettsia Typhi: The Causative Agent of Endemic Typhus
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