Synchronous colorectal liver metastases: focus on the elderly: An Effectiveness Study from Routine Care

Synchronous colorectal liver metastases: focus on the elderly: An Effectiveness Study from Routine Care

Purpose The goal of this study was to analyze the use and the effectiveness of both surgery and different chemotherapies in patients with synchronous colorectal liver metastases (CLMs) ≥70 years compared to younger patients. Methods Survival was analyzed in 456 patients (24.3% ≥70 years) treated for...

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Veröffentlicht in:Langenbeck's archives of surgery 2017-12, Vol.402 (8), p.1223-1232
Hauptverfasser: Albertsmeier, Markus, Engel, Andrea, Guba, Markus O., Stintzing, Sebastian, Schiergens, Tobias S., Schubert-Fritschle, Gabriele, Hölzel, Dieter, Werner, Jens, Angele, Martin K., Engel, Jutta
Format: Artikel
Sprache:eng
Schlagworte:
Abdominal Surgery
Age Factors
Aged
Aged, 80 and over
Antineoplastic Agents - therapeutic use
Cardiac Surgery
Colorectal Neoplasms - mortality
Colorectal Neoplasms - secondary
Colorectal Neoplasms - therapy
Female
General Surgery
Germany
Hepatectomy
Humans
Kaplan-Meier Estimate
Liver Neoplasms - mortality
Liver Neoplasms - secondary
Liver Neoplasms - therapy
Male
Medicine
Medicine & Public Health
Middle Aged
Neoplasms, Multiple Primary - mortality
Neoplasms, Multiple Primary - secondary
Neoplasms, Multiple Primary - therapy
Original Article
Proportional Hazards Models
Survival Rate
Thoracic Surgery
Traumatic Surgery
Treatment Outcome
Vascular Surgery
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Zusammenfassung:Purpose The goal of this study was to analyze the use and the effectiveness of both surgery and different chemotherapies in patients with synchronous colorectal liver metastases (CLMs) ≥70 years compared to younger patients. Methods Survival was analyzed in 456 patients (24.3% ≥70 years) treated for CLM in a single center using Kaplan-Meier estimation of overall survival (OS), calculation of relative survival as estimate for disease-specific survival, and a Cox regression model. Results Complete surgical resections were achieved more often in patients aged
ISSN:1435-2443
1435-2451
DOI:10.1007/s00423-017-1611-8