Vitamin D and symptoms of depression in overweight or obese adults: A cross-sectional study and randomized placebo-controlled trial

•Serum 25-hydroxyvitamin D (25(OH)D) concentrations were not related to depressive symptoms (Beck Depression Inventory [BDI]) in young adults.•Vitamin D supplementation increased 25(OH)D concentrations but had no effect on total BDI scores or BDI subscale scores.•Results remained non-significant aft...

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Veröffentlicht in:	The Journal of steroid biochemistry and molecular biology 2018-03, Vol.177, p.200-208
Hauptverfasser:	Mousa, Aya, Naderpoor, Negar, de Courten, Maximilian P.J., de Courten, Barbora
Format:	Artikel
Sprache:	eng
Schlagworte:	25(OH)D Adult Cross-Sectional Studies Depression Depression - blood Depression - diet therapy Dietary Supplements Double-Blind Method Female Humans Male Obesity Overweight - blood Overweight - diet therapy Randomized trial Vitamin D Vitamin D - administration & dosage Vitamin D - blood Vitamin D Deficiency - blood Vitamin D Deficiency - diet therapy Vitamins - administration & dosage Young Adult
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Zusammenfassung:	•Serum 25-hydroxyvitamin D (25(OH)D) concentrations were not related to depressive symptoms (Beck Depression Inventory [BDI]) in young adults.•Vitamin D supplementation increased 25(OH)D concentrations but had no effect on total BDI scores or BDI subscale scores.•Results remained non-significant after adjustment for covariates and in subgroup analysis of participants with 25(OH)D 0.1). After the 16-week intervention, 25(OH)D concentrations increased in the vitamin D group compared to placebo (56.0±20.8 versus 2.7±13.9 nmol/L, respectively; p
ISSN:	0960-0760 1879-1220
DOI:	10.1016/j.jsbmb.2017.08.002