Swept-source OCT angiography imaging of the macular capillary network in glaucoma

PurposeTo evaluate the macular capillary network density of superficial and deep retinal layers (SRL/DRL) by swept-source optical coherence tomography angiography (OCTA) in patients with primary open angle glaucoma (POAG) and to compare the results with those of normal subjects.MethodIn this prospec...

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Veröffentlicht in:British journal of ophthalmology 2018-04, Vol.102 (4), p.515-519
Hauptverfasser: Akil, Handan, Chopra, Vikas, Al-Sheikh, Mayss, Ghasemi Falavarjani, Khalil, Huang, Alex S, Sadda, SriniVas R, Francis, Brian A
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Sprache:eng
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Zusammenfassung:PurposeTo evaluate the macular capillary network density of superficial and deep retinal layers (SRL/DRL) by swept-source optical coherence tomography angiography (OCTA) in patients with primary open angle glaucoma (POAG) and to compare the results with those of normal subjects.MethodIn this prospective study, 24 eyes of 24 normal individuals and 24 eyes of 24 patients with mild to moderate POAG underwent fovea centred 6×6 mm cube macular OCTA imaging by a swept-source OCTA device (Triton, Topcon, Tokyo, Japan). Quantitative analysis of the retinal vasculature was performed by assessing vessel density (VD) as the ratio of the retinal area occupied by vessels at the SRL and DRL.ResultsThe mean VD (ratio) at the SRL and DRL was statistically significantly lower in patients with POAG (SRL, p
ISSN:0007-1161
1468-2079
DOI:10.1136/bjophthalmol-2016-309816