Dissecting the chloride-nitrate anion transport assay

A systematic study of chloride vs. nitrate selectivity across six anion transporters has revealed a good correlation between the selectivities of their anion binding and membrane transport properties. This work reveals the limitations of the chloride-nitrate exchange assay and shows how new approach...

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2017-08, Vol.53 (66), p.9230-9233
Hauptverfasser: Yang, Yufeng, Wu, Xin, Busschaert, Nathalie, Furuta, Hiroyuki, Gale, Philip A
Format: Artikel
Sprache:eng
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Zusammenfassung:A systematic study of chloride vs. nitrate selectivity across six anion transporters has revealed a good correlation between the selectivities of their anion binding and membrane transport properties. This work reveals the limitations of the chloride-nitrate exchange assay and shows how new approaches can be used to measure anion uniport.
ISSN:1359-7345
1364-548X
DOI:10.1039/c7cc04912a