Continuous Glucose Monitoring Detected Hypoglycaemia in the Treating to Target in Type 2 Diabetes Trial (4-T)

Highlights • Reported frequencies of self-reported hypoglycaemia in clinical trials may significantly underestimate interstitial hypoglycaemic events detected by continuous glucose monitoring. • This highlights risk of minimising important adverse effects of glucose lowering therapies in the light o...

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Veröffentlicht in:	Diabetes research and clinical practice 2017-09, Vol.131, p.161-168
Hauptverfasser:	Levy, JC, Davies, MJ, Holman, RR
Format:	Artikel
Sprache:	eng
Schlagworte:	Blood Glucose - metabolism Blood Glucose Self-Monitoring - methods Clinical trials Continuous glucose monitoring Diabetes Mellitus, Type 1 - blood Diabetes Mellitus, Type 2 - blood Endocrinology & Metabolism Female Humans Hypoglycaemia Hypoglycemia - diagnosis Hypoglycemia - drug therapy Hypoglycemic Agents - therapeutic use Insulin - therapeutic use Insulin therapy Male Middle Aged Type 2 diabetes
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Zusammenfassung:	Highlights • Reported frequencies of self-reported hypoglycaemia in clinical trials may significantly underestimate interstitial hypoglycaemic events detected by continuous glucose monitoring. • This highlights risk of minimising important adverse effects of glucose lowering therapies in the light of associations between hypoglycaemia and major cardiovascular events.
ISSN:	0168-8227 1872-8227
DOI:	10.1016/j.diabres.2017.01.022