Antifungal Activity of Alkaloids Against Candida albicans
Candida albicans is a pathogen in the mouth responsible for opportunistic infections that are usually harmless. Natural products have been used to develop several drugs, mostly anticancer and anti-infective agents. Among these, alkaloids have been studied for their medicinal properties. In this stud...
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Veröffentlicht in: | Journal of the California Dental Association 2016-08, Vol.44 (8), p.493-498 |
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container_title | Journal of the California Dental Association |
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creator | Noguti, Juliana Rajinia, Mersedeh Zancope, Bruna Raquel Marquezin, Maria Carolina Salome Seleem, Dalia Pardi, Vanessa Murata, Ramiro M |
description | Candida albicans is a pathogen in the mouth responsible for opportunistic
infections that are usually harmless. Natural products have been used to develop
several drugs, mostly anticancer and anti-infective agents. Among these, alkaloids
have been studied for their medicinal properties. In this study, we examined their
antifungal activity against C. albicans in vitro. Among the alkaloids studied in this
work, berberine hydrochloride showed the best activity against C. albicans. |
doi_str_mv | 10.1080/19424396.2016.12221046 |
format | Article |
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infections that are usually harmless. Natural products have been used to develop
several drugs, mostly anticancer and anti-infective agents. Among these, alkaloids
have been studied for their medicinal properties. In this study, we examined their
antifungal activity against C. albicans in vitro. Among the alkaloids studied in this
work, berberine hydrochloride showed the best activity against C. albicans.</description><identifier>ISSN: 1043-2256</identifier><identifier>ISSN: 1942-4396</identifier><identifier>EISSN: 1942-4396</identifier><identifier>DOI: 10.1080/19424396.2016.12221046</identifier><identifier>PMID: 28737849</identifier><language>eng</language><publisher>United States</publisher><subject>Alkaloids - pharmacology ; Antifungal Agents - pharmacology ; Candida albicans - drug effects ; Dentistry ; Humans ; Microbial Sensitivity Tests</subject><ispartof>Journal of the California Dental Association, 2016-08, Vol.44 (8), p.493-498</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c226t-61b686a2e79ebe8dacefd476447bbcef77bc8a2b26f62ef9dde6b621978e9aa53</citedby><cites>FETCH-LOGICAL-c226t-61b686a2e79ebe8dacefd476447bbcef77bc8a2b26f62ef9dde6b621978e9aa53</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28737849$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Noguti, Juliana</creatorcontrib><creatorcontrib>Rajinia, Mersedeh</creatorcontrib><creatorcontrib>Zancope, Bruna Raquel</creatorcontrib><creatorcontrib>Marquezin, Maria Carolina Salome</creatorcontrib><creatorcontrib>Seleem, Dalia</creatorcontrib><creatorcontrib>Pardi, Vanessa</creatorcontrib><creatorcontrib>Murata, Ramiro M</creatorcontrib><title>Antifungal Activity of Alkaloids Against Candida albicans</title><title>Journal of the California Dental Association</title><addtitle>J Calif Dent Assoc</addtitle><description>Candida albicans is a pathogen in the mouth responsible for opportunistic
infections that are usually harmless. Natural products have been used to develop
several drugs, mostly anticancer and anti-infective agents. Among these, alkaloids
have been studied for their medicinal properties. In this study, we examined their
antifungal activity against C. albicans in vitro. Among the alkaloids studied in this
work, berberine hydrochloride showed the best activity against C. albicans.</description><subject>Alkaloids - pharmacology</subject><subject>Antifungal Agents - pharmacology</subject><subject>Candida albicans - drug effects</subject><subject>Dentistry</subject><subject>Humans</subject><subject>Microbial Sensitivity Tests</subject><issn>1043-2256</issn><issn>1942-4396</issn><issn>1942-4396</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kM1OwzAQhC0EoqXwClWOXFLsjeufY1RBQarEBc7WOrYrQ5qUOEHq29OoLacZaWZ2pY-QOaMLRhV9YpoDL7RYAGViwQCAUS6uyHQM8jG5PnrKixxgKSbkLqUvSpdacnVLJqBkIRXXU6LLpo9haLZYZ2XVx9_YH7I2ZGX9jXUbXcrKLcYm9dkKGxcdZljbWGGT7slNwDr5h7POyOfL88fqNd-8r99W5SavAESfC2aFEgheam-9clj54LgUnEtrj15KWykECyII8EE754UVwLRUXiMuixl5PN3dd-3P4FNvdjFVvq6x8e2QDNNQMAajzIg4VauuTanzwey7uMPuYBg1IzZzwWZGbOaC7Ticn38Mdufd_-zCqfgDm6poOw</recordid><startdate>201608</startdate><enddate>201608</enddate><creator>Noguti, Juliana</creator><creator>Rajinia, Mersedeh</creator><creator>Zancope, Bruna Raquel</creator><creator>Marquezin, Maria Carolina Salome</creator><creator>Seleem, Dalia</creator><creator>Pardi, Vanessa</creator><creator>Murata, Ramiro M</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201608</creationdate><title>Antifungal Activity of Alkaloids Against Candida albicans</title><author>Noguti, Juliana ; Rajinia, Mersedeh ; Zancope, Bruna Raquel ; Marquezin, Maria Carolina Salome ; Seleem, Dalia ; Pardi, Vanessa ; Murata, Ramiro M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c226t-61b686a2e79ebe8dacefd476447bbcef77bc8a2b26f62ef9dde6b621978e9aa53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Alkaloids - pharmacology</topic><topic>Antifungal Agents - pharmacology</topic><topic>Candida albicans - drug effects</topic><topic>Dentistry</topic><topic>Humans</topic><topic>Microbial Sensitivity Tests</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Noguti, Juliana</creatorcontrib><creatorcontrib>Rajinia, Mersedeh</creatorcontrib><creatorcontrib>Zancope, Bruna Raquel</creatorcontrib><creatorcontrib>Marquezin, Maria Carolina Salome</creatorcontrib><creatorcontrib>Seleem, Dalia</creatorcontrib><creatorcontrib>Pardi, Vanessa</creatorcontrib><creatorcontrib>Murata, Ramiro M</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of the California Dental Association</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Noguti, Juliana</au><au>Rajinia, Mersedeh</au><au>Zancope, Bruna Raquel</au><au>Marquezin, Maria Carolina Salome</au><au>Seleem, Dalia</au><au>Pardi, Vanessa</au><au>Murata, Ramiro M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Antifungal Activity of Alkaloids Against Candida albicans</atitle><jtitle>Journal of the California Dental Association</jtitle><addtitle>J Calif Dent Assoc</addtitle><date>2016-08</date><risdate>2016</risdate><volume>44</volume><issue>8</issue><spage>493</spage><epage>498</epage><pages>493-498</pages><issn>1043-2256</issn><issn>1942-4396</issn><eissn>1942-4396</eissn><abstract>Candida albicans is a pathogen in the mouth responsible for opportunistic
infections that are usually harmless. Natural products have been used to develop
several drugs, mostly anticancer and anti-infective agents. Among these, alkaloids
have been studied for their medicinal properties. In this study, we examined their
antifungal activity against C. albicans in vitro. Among the alkaloids studied in this
work, berberine hydrochloride showed the best activity against C. albicans.</abstract><cop>United States</cop><pmid>28737849</pmid><doi>10.1080/19424396.2016.12221046</doi><tpages>6</tpages></addata></record> |
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issn | 1043-2256 1942-4396 1942-4396 |
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source | MEDLINE; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
subjects | Alkaloids - pharmacology Antifungal Agents - pharmacology Candida albicans - drug effects Dentistry Humans Microbial Sensitivity Tests |
title | Antifungal Activity of Alkaloids Against Candida albicans |
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