Antifungal Activity of Alkaloids Against Candida albicans

Candida albicans is a pathogen in the mouth responsible for opportunistic infections that are usually harmless. Natural products have been used to develop several drugs, mostly anticancer and anti-infective agents. Among these, alkaloids have been studied for their medicinal properties. In this stud...

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Veröffentlicht in:Journal of the California Dental Association 2016-08, Vol.44 (8), p.493-498
Hauptverfasser: Noguti, Juliana, Rajinia, Mersedeh, Zancope, Bruna Raquel, Marquezin, Maria Carolina Salome, Seleem, Dalia, Pardi, Vanessa, Murata, Ramiro M
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container_end_page 498
container_issue 8
container_start_page 493
container_title Journal of the California Dental Association
container_volume 44
creator Noguti, Juliana
Rajinia, Mersedeh
Zancope, Bruna Raquel
Marquezin, Maria Carolina Salome
Seleem, Dalia
Pardi, Vanessa
Murata, Ramiro M
description Candida albicans is a pathogen in the mouth responsible for opportunistic infections that are usually harmless. Natural products have been used to develop several drugs, mostly anticancer and anti-infective agents. Among these, alkaloids have been studied for their medicinal properties. In this study, we examined their antifungal activity against C. albicans in vitro. Among the alkaloids studied in this work, berberine hydrochloride showed the best activity against C. albicans.
doi_str_mv 10.1080/19424396.2016.12221046
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subjects Alkaloids - pharmacology
Antifungal Agents - pharmacology
Candida albicans - drug effects
Dentistry
Humans
Microbial Sensitivity Tests
title Antifungal Activity of Alkaloids Against Candida albicans
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