Antifungal Activity of Alkaloids Against Candida albicans

Candida albicans is a pathogen in the mouth responsible for opportunistic infections that are usually harmless. Natural products have been used to develop several drugs, mostly anticancer and anti-infective agents. Among these, alkaloids have been studied for their medicinal properties. In this stud...

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Veröffentlicht in:	Journal of the California Dental Association 2016-08, Vol.44 (8), p.493-498
Hauptverfasser:	Noguti, Juliana, Rajinia, Mersedeh, Zancope, Bruna Raquel, Marquezin, Maria Carolina Salome, Seleem, Dalia, Pardi, Vanessa, Murata, Ramiro M
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkaloids - pharmacology Antifungal Agents - pharmacology Candida albicans - drug effects Dentistry Humans Microbial Sensitivity Tests
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Candida albicans is a pathogen in the mouth responsible for opportunistic infections that are usually harmless. Natural products have been used to develop several drugs, mostly anticancer and anti-infective agents. Among these, alkaloids have been studied for their medicinal properties. In this study, we examined their antifungal activity against C. albicans in vitro. Among the alkaloids studied in this work, berberine hydrochloride showed the best activity against C. albicans.
ISSN:	1043-2256 1942-4396 1942-4396
DOI:	10.1080/19424396.2016.12221046