Efficient Monitoring of Biotechnological Processes by Means of Titration

In this paper, the author demonstrates with examples how simple titrimetric techniques can be applied to efficient process control. Important process parameters, such as cell densities and product concentrations, are computed or estimated on the basis of titrimetric data. Great importance was attached to keeping applications as simple as possible. So, it is not required that biomass be separated prior to analysis. With that a source of disturbance can be minimized.