Kinetics of DNA elongation
A mathematical model of the DNA elongation stage is proposed, and a formula for calculating the characteristic time of doubling a DNA strand consisting of a large numbers of nucleotides was derived. It is shown that, when the number of nucleotides is greater than 50, it is fair to use a linear depen...
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| Veröffentlicht in: | Doklady. Biochemistry and biophysics 2017-05, Vol.474 (1), p.189-192 |
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| container_end_page | 192 |
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| container_issue | 1 |
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| container_title | Doklady. Biochemistry and biophysics |
| container_volume | 474 |
| creator | Bykov, V. I. Lukovenkov, A. V. Varfolomeev, S. D. |
| description | A mathematical model of the DNA elongation stage is proposed, and a formula for calculating the characteristic time of doubling a DNA strand consisting of a large numbers of nucleotides was derived. It is shown that, when the number of nucleotides is greater than 50, it is fair to use a linear dependence of the elongation time on the number of nucleotides. Calculations of the DNA elongation time for a number of organisms are given. |
| doi_str_mv | 10.1134/S1607672917030061 |
| format | Article |
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I. ; Lukovenkov, A. V. ; Varfolomeev, S. D.</creator><creatorcontrib>Bykov, V. I. ; Lukovenkov, A. V. ; Varfolomeev, S. D.</creatorcontrib><description>A mathematical model of the DNA elongation stage is proposed, and a formula for calculating the characteristic time of doubling a DNA strand consisting of a large numbers of nucleotides was derived. It is shown that, when the number of nucleotides is greater than 50, it is fair to use a linear dependence of the elongation time on the number of nucleotides. Calculations of the DNA elongation time for a number of organisms are given.</description><identifier>ISSN: 1607-6729</identifier><identifier>EISSN: 1608-3091</identifier><identifier>DOI: 10.1134/S1607672917030061</identifier><identifier>PMID: 28726097</identifier><language>eng</language><publisher>Moscow: Pleiades Publishing</publisher><subject>Biochemistry ; Biological and Medical Physics ; Biomedical and Life Sciences ; Biophysics ; Deoxyribonucleic acid ; DNA ; DNA - biosynthesis ; DNA - genetics ; Elongation ; Kinetics ; Life Sciences ; Mathematical models ; Models, Biological ; Molecular Biology ; Nucleotides</subject><ispartof>Doklady. 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Calculations of the DNA elongation time for a number of organisms are given.</description><subject>Biochemistry</subject><subject>Biological and Medical Physics</subject><subject>Biomedical and Life Sciences</subject><subject>Biophysics</subject><subject>Deoxyribonucleic acid</subject><subject>DNA</subject><subject>DNA - biosynthesis</subject><subject>DNA - genetics</subject><subject>Elongation</subject><subject>Kinetics</subject><subject>Life Sciences</subject><subject>Mathematical models</subject><subject>Models, Biological</subject><subject>Molecular Biology</subject><subject>Nucleotides</subject><issn>1607-6729</issn><issn>1608-3091</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp1kE9PwzAMxSMEYmPwAeCAJnHhUnCcNGmP0_grJjgA5yrJkqlT146kPfDtSdlACMTJlt_Pz9Yj5JjCBaWMXz5TAVJIzKkEBiDoDhnGUZYwyOnuZy-TXh-QgxCWAAjI0n0ywEyigFwOyclDWdu2NGHcuPHV42Rsq6ZeqLZs6kOy51QV7NG2jsjrzfXL9C6ZPd3eTyezxDCJbSI4CM6ZFpZljGYGHHLIlVZOg0u1dKBVKhGlUVoazuUcqbMWMmfmGWYpG5Hzje_aN2-dDW2xKoOxVaVq23ShoDlSigIZi-jZL3TZdL6O3_UUQMqR8UjRDWV8E4K3rlj7cqX8e0Gh6IMr_gQXd063zp1e2fn3xldSEcANEKJUL6z_cfpf1w_0CXOh</recordid><startdate>20170501</startdate><enddate>20170501</enddate><creator>Bykov, V. 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| ispartof | Doklady. Biochemistry and biophysics, 2017-05, Vol.474 (1), p.189-192 |
| issn | 1607-6729 1608-3091 |
| language | eng |
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| source | MEDLINE; SpringerLink Journals |
| subjects | Biochemistry Biological and Medical Physics Biomedical and Life Sciences Biophysics Deoxyribonucleic acid DNA DNA - biosynthesis DNA - genetics Elongation Kinetics Life Sciences Mathematical models Models, Biological Molecular Biology Nucleotides |
| title | Kinetics of DNA elongation |
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