Kinetics of DNA elongation

Kinetics of DNA elongation

A mathematical model of the DNA elongation stage is proposed, and a formula for calculating the characteristic time of doubling a DNA strand consisting of a large numbers of nucleotides was derived. It is shown that, when the number of nucleotides is greater than 50, it is fair to use a linear depen...

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Veröffentlicht in:Doklady. Biochemistry and biophysics 2017-05, Vol.474 (1), p.189-192
Hauptverfasser: Bykov, V. I., Lukovenkov, A. V., Varfolomeev, S. D.
Format: Artikel
Sprache:eng
Schlagworte:
Biochemistry
Biological and Medical Physics
Biomedical and Life Sciences
Biophysics
Deoxyribonucleic acid
DNA
DNA - biosynthesis
DNA - genetics
Elongation
Kinetics
Life Sciences
Mathematical models
Models, Biological
Molecular Biology
Nucleotides
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Beschreibung
Zusammenfassung:A mathematical model of the DNA elongation stage is proposed, and a formula for calculating the characteristic time of doubling a DNA strand consisting of a large numbers of nucleotides was derived. It is shown that, when the number of nucleotides is greater than 50, it is fair to use a linear dependence of the elongation time on the number of nucleotides. Calculations of the DNA elongation time for a number of organisms are given.
ISSN:1607-6729
1608-3091
DOI:10.1134/S1607672917030061