Complete canine spinal cord transection model： a large animal model for the translational research of spinal cord regeneration

Traumatic spinal cord injury （SCI） usually results in devastating neurologic deficits and disability. In the United States,approximately 12,500 new cases are reported each year, while an estimated 100,000–140,000 new cases occur every year in China （National Spinal Cord Injury Statistical Center, 2016）.Spinal cord injuries are highly disabling and primarily affect young adults, and therefore create great psychological and financial burden on the affected individuals and their families.