The depletion of MARVELD1 leads to murine placenta accreta via integrin β4‐dependent trophoblast cell invasion

The placenta is a remarkable organ, it serves as the interface between the mother and the fetus. Proper invasion of trophoblast cells is required for a successful pregnancy. Previous studies have found that the adhesion molecule integrin β4 plays important roles during trophoblast cell invasion. Her...

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Veröffentlicht in:	Journal of cellular physiology 2018-03, Vol.233 (3), p.2257-2269
Hauptverfasser:	Chen, Yue, Zhang, Hui, Han, Fang, Yue, Lei, Qiao, Chunxiao, Zhang, Yao, Dou, Peng, Liu, Weizhe, Li, Yu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Adhesion cell invasion Cell Line, Tumor Cell Movement Disease Models, Animal Female Gene Expression Regulation Genetic Predisposition to Disease Humans Integrin beta4 - genetics Integrin beta4 - metabolism integrin β4 MARVELD1 Membrane Proteins - deficiency Membrane Proteins - genetics Membrane Proteins - metabolism Mice Mice, Inbred C57BL Mice, Knockout Microtubule-Associated Proteins - deficiency Microtubule-Associated Proteins - genetics Microtubule-Associated Proteins - metabolism NIH 3T3 Cells Phenotype Placenta Accreta - genetics Placenta Accreta - metabolism Placenta Accreta - pathology placenta accrete Pregnancy Promoter Regions, Genetic Signal Transduction trophoblast cell Trophoblasts - metabolism Trophoblasts - pathology
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