Nanostructures: Enhanced Differentiation of Human Embryonic Stem Cells Toward Definitive Endoderm on Ultrahigh Aspect Ratio Nanopillars (Adv. Funct. Mater. 6/2016)

Nanostructures: Enhanced Differentiation of Human Embryonic Stem Cells Toward Definitive Endoderm on Ultrahigh Aspect Ratio Nanopillars (Adv. Funct. Mater. 6/2016)

N. Gadegaard and co‐workers report on page 815 a nanofabricated thermoplastic substrate with ultra‐high aspect ratio nanopillars. This substrate, formed via injection molding, is used to enhance the differentiation of human embryonic stem cells. The nanostructured surface results in a softer substra...

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Veröffentlicht in:Advanced functional materials 2016-02, Vol.26 (6), p.814-814
Hauptverfasser: Rasmussen, Camilla Holzmann, Reynolds, Paul M., Petersen, Dorthe Roenn, Hansson, Mattias, McMeeking, Robert M., Dufva, Martin, Gadegaard, Nikolaj
Format: Artikel
Sprache:eng
Schlagworte:
human embryonic stem cells
injection moulding
mechanotransduction
nanostructures
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Zusammenfassung:N. Gadegaard and co‐workers report on page 815 a nanofabricated thermoplastic substrate with ultra‐high aspect ratio nanopillars. This substrate, formed via injection molding, is used to enhance the differentiation of human embryonic stem cells. The nanostructured surface results in a softer substrate, which mimics the natural extracellular environment.
ISSN:1616-301X
1616-3028
DOI:10.1002/adfm.201670038