Screening for Oral Cancer Using Electrochemical Telomerase Assay

Screening for Oral Cancer Using Electrochemical Telomerase Assay

Electrochemical telomerase assay (ECTA) developed by our group was evaluated in an oral cancer screening using exfoliated oral cells and tissues obtained from patients of oral cancer, mucosa associated disease, or healthy volunteers. Telomerase activity from ECTA is correlated with hTERT mRNA expres...

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Veröffentlicht in:Electroanalysis (New York, N.Y.) N.Y.), 2016-03, Vol.28 (3), p.503-507
Hauptverfasser: Hayakawa, Mana, Sato, Shinobu, Diala, Irmina, Kodama, Masaaki, Tomoeda-Mori, Kumiko, Haraguchi, Kazuya, Tominaga, Kazuhiro, Takenaka, Shigeori
Format: Artikel
Sprache:eng
Schlagworte:
Assaying
Cancer
Correlation
electrochemical assay
Gene expression
hTERT gene
oral cancer screening
Real time
Receivers
Screening
Telomerase
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Beschreibung
Zusammenfassung:Electrochemical telomerase assay (ECTA) developed by our group was evaluated in an oral cancer screening using exfoliated oral cells and tissues obtained from patients of oral cancer, mucosa associated disease, or healthy volunteers. Telomerase activity from ECTA is correlated with hTERT mRNA expression level using a real‐time PCR and was increasing in the following order: healthy volunteer group
ISSN:1040-0397
1521-4109
DOI:10.1002/elan.201500426