HLA markers associated with progression to AIDS are also associated with susceptibility to cytomegalovirus retinitis

HLA markers associated with progression to AIDS are also associated with susceptibility to cytomegalovirus retinitis

The frequency of HLA markers associated with rapid progression from HIV infection to AIDS was evaluated in Brazilian patients with AIDS exhibiting or not exhibiting cytomegalovirus retinitis (CMV-R). A total of 124 AIDS patients (44 with and 80 without CMV-R) were studied. HLA markers associated wit...

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Veröffentlicht in:AIDS (London) 2003-09, Vol.17 (14), p.2133-2135
Hauptverfasser: Fernandes, APM, Goncalves, MAG, Zavanella, R B, Figueiredo, JFC, Donadi, E A, Rodrigues, MLV
Format: Artikel
Sprache:eng
Schlagworte:
histocompatibility antigen HLA
Human cytomegalovirus
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Zusammenfassung:The frequency of HLA markers associated with rapid progression from HIV infection to AIDS was evaluated in Brazilian patients with AIDS exhibiting or not exhibiting cytomegalovirus retinitis (CMV-R). A total of 124 AIDS patients (44 with and 80 without CMV-R) were studied. HLA markers associated with rapid progression to AIDS were significantly increased in the CMV-R group compared with those without retinitis. The presence of these HLA markers may simultaneously predispose to AIDS and CMV-R.
ISSN:0269-9370
DOI:10.1097/01.aids.0000088186.01779.1c