Risk of misclassification with a non-fasting lipid profile in secondary cardiovascular prevention

Routinely fasting is not necessary for measuring the lipid profile according to the latest European consensus. However, LDL-C tends to be lower in the non-fasting state with risk of misclassification. The extent of misclassification in secondary cardiovascular prevention with a non-fasting lipid pro...

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Veröffentlicht in:	Clinica chimica acta 2017-09, Vol.472, p.90-95
Hauptverfasser:	Klop, Boudewijn, Hartong, Simone C.C., Vermeer, Henricus J., Schoofs, Mariette W.C.J., Kofflard, Marcel J.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Apolipoprotein B Blood Chemical Analysis - standards Cardiovascular Diseases - blood Cardiovascular Diseases - prevention & control Fasting - blood Female Humans LDL-C Lipids - blood Male Middle Aged Misclassification Non-fasting Non-HDL-C Predictive Value of Tests Reference Values Treatment target
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Zusammenfassung:	Routinely fasting is not necessary for measuring the lipid profile according to the latest European consensus. However, LDL-C tends to be lower in the non-fasting state with risk of misclassification. The extent of misclassification in secondary cardiovascular prevention with a non-fasting lipid profile was investigated. 329 patients on lipid lowering therapy for secondary cardiovascular prevention measured a fasting and non-fasting lipid profile. Cut-off values for LDL-C, non-HDL-C and apolipoprotein B were set at
ISSN:	0009-8981 1873-3492
DOI:	10.1016/j.cca.2017.07.005