Challenge to Coordinate Harmonization Activities on an International Level

In the US, a National Institutes of Health-sponsored standardization program developed a reference measurement procedure that was listed by the Joint Committee for Traceability in Laboratory Medicine (JCTLM), and qualified a panel of pooled serum reference materials for use as secondary reference materials for calibration traceability of medical laboratory measurement procedures. [...]the stocks of the World Health Organization (WHO) reference reagent intended for use to calibrate immunoassays were exhausted and replaced with a new international standard of pure substance C-peptide intended for use by immunoassays. Author Contributions: All authors confirmed they have contributed to the intellectual content of this paper and have met the following3 requirements: (a) significant contributions to the conception and design, acquisition of data, or analysis and interpretation of data; (b) drafting or revising the article for intellectual content; and (c) final approval of the published article.