Inflammatory and Nutritional Serum Markers as Predictors of Peri-operative Morbidity and Survival in Ovarian Cancer

To identify preoperative nutritional and inflammatory markers that predict perioperative outcomes in patients with ovarian cancer (OC). Fifty patients who underwent primary debulking for advanced (stage III/IV) OC were selected from a cohort of patients who underwent surgery between 2002 and 2009. W...

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Veröffentlicht in:	Anticancer research 2017-07, Vol.37 (7), p.3673-3677
Hauptverfasser:	Kumar, Amanika, Torres, Michelle L, Cliby, William A, Kalli, Kimberly R, Bogani, Giorgio, Aletti, Giovanni, Nitschmann, Caroline C, Multinu, Francesco, Weaver, Amy L, Block, Matthew S, Mariani, Andrea
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Biomarkers - blood Biomarkers - metabolism C-Reactive Protein - metabolism Female Humans Inflammation - blood Inflammation - metabolism Interleukin-6 - blood Interleukin-6 - metabolism Nutritional Status - physiology Ovarian Neoplasms - blood Ovarian Neoplasms - metabolism Ovarian Neoplasms - surgery Perioperative Period Pilot Projects Serum Albumin - metabolism
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Zusammenfassung:	To identify preoperative nutritional and inflammatory markers that predict perioperative outcomes in patients with ovarian cancer (OC). Fifty patients who underwent primary debulking for advanced (stage III/IV) OC were selected from a cohort of patients who underwent surgery between 2002 and 2009. We analyzed C-reactive protein (CRP), interleukin-6 (IL6) and albumin and their impact on mortality and surgical outcomes. Two patients were excluded since they did not have adequate measurements of CRP and IL6. Among the remaining patients, 25 (52%) were ≥70 years old. Nine (19%), 12 (25%) and 12 (25%) patients had low serum albumin (
ISSN:	0250-7005 1791-7530
DOI:	10.21873/anticanreS.11738