Recent Advances in Structure-Based Drug Design Targeting Class A G Protein-Coupled Receptors Utilizing Crystal Structures and Computational Simulations

G protein-coupled receptors (GPCRs) represent the largest and most physiologically important integral membrane protein family, and these receptors respond to a wide variety of physiological and environmental stimuli. GPCRs are among the most critical therapeutic targets for numerous human diseases,...

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Veröffentlicht in:Journal of medicinal chemistry 2018-01, Vol.61 (1), p.1-46
Hauptverfasser: Lee, Yoonji, Basith, Shaherin, Choi, Sun
Format: Artikel
Sprache:eng
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