A zinc oxide‐modified hydroxyapatite‐based cement facilitated new crystalline‐stoichiometric and amorphous apatite precipitation on dentine

Aim To evaluate the remineralization ability of two endodontic sealer cements. Methodology Mid‐coronal dentine surfaces were subjected to: (i) 37% phosphoric acid (PA) or (ii) 0.5 mol L−1 ethylenediaminetetraacetic acid (EDTA) conditioning prior to the application of two experimental hydroxyapatite‐based cements, containing sodium hydroxide (calcypatite) or zinc oxide oxiapatite respectively. Samples were stored in simulated body fluid for 24 h or 21 days. Remineralization of the dentine surfaces were studied by Raman spectroscopy (mapping with K‐means cluster and hierarchical cluster analysis) was undertaken. Nanoroughness and collagen fibril width measurements were performed with an atomic force microscopy. ANOVA and Student–Newman–Keuls test were performed (α=0.05). Results Phosphoric acid+oxiapatite promoted both the highest dentine mineralization (P