Tramadol may increase the efficacy of therapeutic plasma exchange in anti-NMDAR encephalitis

•The first-line treatments of anti-NMDAR encephalitis often take several weeks to months to control debilitating symptoms.•Tramadol possibly increases the efficacy of PLEX in anti-NMDAR encephalitis and leads to a shorter duration of the illness.•Tramadol could have therapeutic effect on dyskinesia...

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Veröffentlicht in:	Clinical neurology and neurosurgery 2017-09, Vol.160, p.38-39
Hauptverfasser:	Dengler, Bradley A., Kitchen, Deanna, Seifi, Ali
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anti-N-Methyl-D-Aspartate Receptor Encephalitis - complications Anti-N-Methyl-D-Aspartate Receptor Encephalitis - therapy Anti-NMDAR encephalitis Apheresis Autoimmune encephalitis Combined Modality Therapy Dyskinesia Dyskinesias - etiology Dyskinesias - therapy Encephalitis Fatigue Female Females Glutamic acid receptors Humans Immunoglobulins Immunotherapy N-Methyl-D-aspartic acid receptors Neuro critical care Neurology Patients Plasma Plasma Exchange Psychosis Schizophrenia Side effects Tramadol Tramadol - administration & dosage Tramadol - pharmacology
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Zusammenfassung:	•The first-line treatments of anti-NMDAR encephalitis often take several weeks to months to control debilitating symptoms.•Tramadol possibly increases the efficacy of PLEX in anti-NMDAR encephalitis and leads to a shorter duration of the illness.•Tramadol could have therapeutic effect on dyskinesia in anti-NMDAR encephalitis.
ISSN:	0303-8467 1872-6968
DOI:	10.1016/j.clineuro.2017.05.024