Severe but reversible neuropathy and encephalopathy due to vitamin E deficiency

Highlights • We report a case of severe vitamin E deficiency due to pancreatic exocrine insufficiency. • Vitamin E deficiency can produce sensory ataxic neuropathy and cognitive decline. • Supplementation in high-dose vitamin E produced rapid significant improvement of neuropathy and cognition....

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Veröffentlicht in:	Clinical neurology and neurosurgery 2017-09, Vol.160, p.19-20
Hauptverfasser:	Wysota, Barbara, Michael, Sophia, Hiew, Fu Liong, Dawson, Charlotte, Rajabally, Yusuf A
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdomen Ataxia Autoimmune diseases Biopsy Cognitive ability Cognitive Dysfunction - drug therapy Cognitive Dysfunction - etiology Diabetes Diabetic neuropathy Encephalopathy Exocrine Pancreatic Insufficiency - complications Family medical history Female Humans Middle Aged Mutation Neurology Neuropathy Neurosurgery Peripheral Nervous System Diseases - diagnosis Peripheral Nervous System Diseases - drug therapy Peripheral Nervous System Diseases - etiology Sensory Vitamin D Vitamin deficiency Vitamin E Vitamin E - administration & dosage Vitamin E - pharmacology Vitamin E Deficiency - complications Vitamin E Deficiency - etiology Vitamins
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Zusammenfassung:	Highlights • We report a case of severe vitamin E deficiency due to pancreatic exocrine insufficiency. • Vitamin E deficiency can produce sensory ataxic neuropathy and cognitive decline. • Supplementation in high-dose vitamin E produced rapid significant improvement of neuropathy and cognition.
ISSN:	0303-8467 1872-6968
DOI:	10.1016/j.clineuro.2017.06.005