Morph or Move? How Distinct Endothelial Cell Responses to Blood Flow Shape Vascular Networks

Blood vessel shape is malleable and dynamically regulated. In two recent papers in Nature Cell Biology, Jin et al. (2017) and Sugden et al. (2017) show that endoglin alters endothelial cell shape or behavior in response to blood flow, thus regulating vessel structure. Blood vessel shape is malleable...

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Veröffentlicht in:	Developmental cell 2017-06, Vol.41 (6), p.574-576
Hauptverfasser:	Franco, Claudio A., Gerhardt, Holger
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blood Vessels - metabolism Blood Vessels - pathology Cell Shape - physiology Endoglin - metabolism Endothelial Cells - cytology Hemodynamics - physiology Humans Signal Transduction - physiology
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Blood vessel shape is malleable and dynamically regulated. In two recent papers in Nature Cell Biology, Jin et al. (2017) and Sugden et al. (2017) show that endoglin alters endothelial cell shape or behavior in response to blood flow, thus regulating vessel structure. Blood vessel shape is malleable and dynamically regulated. In two recent papers in Nature Cell Biology, Jin et al. (2017) and Sugden et al. (2017) show that endoglin alters endothelial cell shape or behavior in response to blood flow, thus regulating vessel structure.
ISSN:	1534-5807 1878-1551
DOI:	10.1016/j.devcel.2017.06.008